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July 24, 2018

Today's Rundown

Featured Story

Biogen pays $27.5M upfront for 2 AliveGen muscle drugs

Biogen has bolted on a couple of early-stage drug candidates for neuromuscular diseases via a $535 million deal with California startup AliveGen.

Top Stories

Merck posts 96-week doravirine HIV data as PDUFA date nears

Merck has posted 96-week data on an HIV prospect it hopes will replace drugs including Bristol-Myers Squibb’s Sustiva in combination regimens. The update linked Merck’s doravirine to a higher rate of viral suppression than a combination of antiretroviral drugs from AbbVie and Johnson & Johnson.

Bristol-Myers Squibb, Tsinghua University pen drug discovery pact

Bristol-Myers Squibb has teamed up with China’s Tsinghua University to discover drugs that hit novel cancer and autoimmune disease targets. The agreement tasks Tsinghua with discovering therapeutics that Bristol-Myers can then choose to license.

[Sponsored] Q&A with Cardinal Health Regulatory Sciences: Navigating cell and gene therapies through clinical and regulatory hurdles

Gene and cell therapies are at the cutting-edge of biomedical research, promising potentially curative options for a host of disorders such as forms of blindness, blood cancers and inherited diseases.

Gossamer Bio nets $230M in series B to advance portfolio against undisclosed targets

Gossamer Bio netted $230 million in a series B financing round—on the heels of its $100 million launch in January—to accelerate the company’s growth and fund clinical trials of candidates with undisclosed targets in immunology, inflammation, immuno-oncology and fibrosis.

Enzyvant and PerkinElmer to develop gene test for ultrarare Farber disease

Roivant Sciences’ rare disease offshoot, Enzyvant, is partnering up with PerkinElmer Genomics to develop a test for the genetic mutations associated with Farber disease, an ultrarare lysosomal storage disorder.

Synexus debuts new patient registry in U.S. for study of longitudinal brain aging

Synexus, a global site management organization, is partnering with the University of Exeter in the U.K. to launch a registry-based study in the U.S. to better understand how healthy brains age.

Resources

[Whitepaper] Building the Business Case for RIM Transformation

Ready to modernize your RIM environment? Secure buy-in with these tips.

[Whitepaper] How early planning and a unified data platform can cut trial timelines and cost.

Accelerate Clinical Research as Study Complexity Grows

[Whitepaper] Rise in Targeted Therapies Drives Needs for Small Volume Manufacturing

Biologics, orphan drugs, and precision medicine are on the rise, and that means some big changes for drug development and manufacturing companies. What should pharma companies look for when navigating this new era of small-volume manufacturing? Here are some ideas to consider when developing a new manufacturing strategy.

[Whitepaper] eClinical Landscape Study - CRO Report from Tufts Center for the Study of Drug Development

See results from the Tufts eClinical Landscape Study – CRO Report on current data management practices, goals, and challenges for contract research organizations (CROs).

[Whitepaper] Digitizing the Global Life Sciences Supply Chain: The Critical Role of Digital Transaction Management

Life science companies are experiencing a significant transformation in how they bring new products to market.

Events

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