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Today's Rundown

Featured Story

AstraZeneca teams up with Regeneron for obesity-busting drug pact focused on genetics

Though known more for its oncology and diabetes pipeline, AstraZeneca is now entering a new phase in obesity with a research pact penned with Regeneron.

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Top Stories

Biogen's second tau bet in Alzheimer's passes early test, though odds of success remains 'low'

Biogen and partner Ionis Pharmaceuticals said their anti-tau antisense treatment candidate was safe and tolerable in a phase 1b study of patients with mild Alzheimer's disease.

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AbbVie hits go on $1B re-upped Calico deal as the Google life science spin-out continues I-O, neuro push

Seven years ago, AbbVie penned an early-stage deal with Google/Alphabet’s life sciences division Calico: The pair have clearly enjoyed their time together, as they are penning a second extension for that collab.

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Sponsored: Medical Cannabis from Colombia Can Change Lives

Medical cannabis from Colombia can change lives.

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Merck women's health spinout Organon bags preterm labor drug ahead of phase 3

Organon has struck a deal to license the global rights to preterm labor prospect ebopiprant from ObsEva. The Merck spinout is set to pay $25 million upfront and commit to paying up to $475 million in milestones to take control of the prostaglandin F2α receptor antagonist.

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Artios raises $153M to fund DNA damage repair clinical trials

Artios Pharma has raised $153 million to take its DNA damage response (DDR) pipeline deeper into the clinic. The series C positions Artios, which is run by some of the people behind pioneering DDR drug Lynparza, to test the effect of interfering with DNA double-strand break repair processes.  

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Ex-Kiadis CBO takes the wheel at SynOx after $358M Sanofi buyout

As SynOx Therapeutics gears up to test its anti-CSF1R antibody in registrational trials, the Dublin-based biotech is getting a pair of new leaders. Ray Barlow, formerly the chief business officer of Kiadis Pharma, signs on as CEO and Ton Logtenberg, Ph.D. becomes the company’s new non-executive chairman.

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IMIDomics emerges with $16.5M, former Takeda exec at the helm, and a precision approach to inflammatory disease

After 15 years of laying the groundwork, IMIDomics is coming out of the shadows with $16.5 million and a mission to bring precision medicine to inflammatory ailments such as Crohn’s disease, lupus and rheumatoid arthritis.

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Prothena rolls out preclinical data for anti-amyloid Alzheimer's candidate to rival Biogen's Aduhelm

Less than two months after Biogen received the FDA green light for its controversial Alzheimer's drug Aduhelm, competitor Prothena said preclinical studies of its own monoclonal antibody targeting amyloid-beta show that the drug binds to its target with about 11 times more strength than Biogen's does.

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BD fortifies surgical mesh portfolio with acquisition of polymer maker Tepha

With five tuck-in acquisitions already under its belt for the year and no signs of slowing down, BD has made what may be its strongest buyout yet—literally.

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Resources

eBook: Get solutions to market faster

Read Get to Know Cloud Content Management for Life Sciences and learn how to eliminate silos across all workflows, from R&D to commercialization.

Content Hub: Post-Marketing Safety Studies

Learn about key post-marketing safety study solutions, including registries and REMS, and how they can most effectively help meet regulatory requirements and maximize patient access.

Whitepaper: To De-Risk Your Next Trial, Seek Outside Expertise

Engage Independent Expert Endpoint Adjudication and Data Monitoring Committees in a strategic manner to identify methods for retrospective and prospective evaluations that may improve competitive advantage and bolster regulatory submissions.

Whitepaper: Strategies for mitigating supply chain risk in clinical trials

Take a closer look at your supply chain to ensure it delivers with speed, efficiency, and quality — all within budget.

Whitepaper: Evaluating current manufacturing platforms for recombinant AAV production

Choose the right AAV platform for your viral vector-based therapy

E-Book: Digital Therapeutics 101

E-book to get newcomers “up to speed” quickly on digital health and digital therapeutics while also addressing key issues important to those already familiar with the topic.

Content Hub: Process Intensification Resource Center

A one-stop hub for Cytiva resources to support process intesification

Content Hub: Remarque Systems Resource Hub

Remarque Systems consolidates data, then layers on visualization and automated metrics to generate consistent, actionable data insights in real-time. Click here for more info. 

eBrief: Drug Product Process Development: Ensuring a Consistent, High-quality Biologic

Learn about drug product process development challenges and risks, the difference between innovator and biosimilar drug product process development, and more during the drug product process development phase.

Whitepaper: Achieving a Successful Drug Product Technology Transfer

Get insights on key considerations for a successful tech transfer process for manufacturing a biologic drug product, including a case study on overcoming challenges in a process transfer for a sterile diluent.

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