Alexion dumps ex-Achillion C3G program after seeing phase 2 data

By Nick Paul Taylor

Alexion has scrapped development of the lead asset acquired in its $930 million takeover of Achillion Pharmaceuticals in one indication. The action follows a “suboptimal” clinical response in two phase 2 trials in C3 glomerulopathy (C3G) patients that were expected to support global regulatory talks. 

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Sponsored: FROM CHOLERA TO COVID-19: How integrated data visualizations inform decisions and impact actions

By PerkinElmer, Inc

How integrated data visualizations inform decisions and impact actions. Data visualization was first used to recognize disease patterns in the 1854 London cholera outbreak. It is even more essential today.

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Novartis, Sangamo team up on genetic meds for autism in $75M deal

By Amirah Al Idrus

Sangamo’s struck another CNS deal—this time, it’s teaming up with Novartis on neurodevelopmental disorders, including autism spectrum disorder and intellectual disability. $75 million is changing hands upfront, but Sangamo could pick up an additional $720 million in milestones over the three-year deal.

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F-star set to land Nasdaq listing through Spring Bank merger

By Nick Paul Taylor

F-star Therapeutics is set to merge with Spring Bank Pharmaceuticals, giving it a Nasdaq listing to support the advance of its pipeline of bispecific antibodies. The merger comes months after a death in Spring Bank’s phase 2b hepatitis B trial torpedoed the biotech’s stock. 

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Looking beyond COVID-19's spike protein for the next wave of vaccines

By Angus Liu

Most ongoing vaccine development efforts against the novel coronavirus focus on the spike protein on the surface of SARS-CoV-2. But a team led by immuno-oncology specialist TScan Therapeutics found that memory CD8+ T cells from recovered patients mainly target sites outside of the spike protein.

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Sorrento picks up color-changing COVID-19 saliva test built by Columbia University fertility clinic

By Conor Hale

The single-step test aims to provide an easy-to-read result in less than 30 minutes just about anywhere.

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Whitepaper: Learn How to Navigate Pediatric Clinical Trials Under the New RACE Act

Sponsored by: PRA Health Sciences

Collaboration across the industry will be key to meeting the demands of the RACE Act and ensuring pediatric patients receive the care and treatments they need.

eBook: Cambrex eBook - Small molecules: 2020 vision

Sponsored by: Cambrex

The industry trend of outsourcing to CDMOs continues. With more services, capabilities, facilities, and employees than ever before, our experts have contributed more articles to our biggest eBook yet.

White Paper: Patient Switching Behaviors Impact on Adherence and Engagement: A Predictive Analytics and Machine Learning Approach to Improving Hub Performance and Patient Outcomes

Sponsored by: EVERSANA

How predictive analytics and machine learning have the potential to transform healthcare by predicting “Patient Switching Behaviors.”

Whitepaper: You've Decided on a Multiparticulate Dosage Form. Now What?

Sponsored by: Recro Gainesville

Wurster processing is a versatile technique for developing and manufacturing multiparticulates for modified release dosage forms. Read this whitepaper to determine whether Wurster processing is the right option for your project.

Case Study: Establishing Parameters for Success

Sponsored by: Catalent

Learn about a real-world example of how clinical supply management expertise was applied to overcome inventory challenges for a complex, global study.

Fact Sheet: Forecasting to Optimize Clinical Trial Supply Management

Sponsored by: Catalent

Whether a study is simple or highly complex, forecasting and simulation reports serve as data driven communication tools to help minimize risks and keep the study on track. Learn more about forecasting solutions for informed decision making and supporting contingency planning for clinical study.

eBook: Expecting the Unexpected: Strategies for Efficient Clinical Supply Management and Forecasting

Sponsored by: Catalent

Learn how to drive excellence within the forecasting process and utilize forecasting throughout the clinical study to better plan clinical supply budgets and project timelines. Explore how to identify potential supply-related issues before they can negatively impact your study.