Verily to move HQ to Texas

Today’s Big News

Jul 30, 2024

Pfizer tacks on $1B to 2024 revenue outlook amid cost-cutting drive


Pfizer takes $230M hit after axing failed DMD gene therapy—and tosses out RSV combo vaccine


Incyte drops pair of PD-L1 drugs as part of 2nd pipeline clear-out this year


Verily to relocate its HQ from San Francisco to Dallas


Eli Lilly keeps up Olympics push, donating $5,000 for each Team USA milestone at Paris Games


Merck mystified by sudden 'step down' in Gardasil sales in China

 

Featured

Pfizer tacks on $1B to 2024 revenue outlook amid cost-cutting drive

For the first time since its sales peaked during the pandemic, Pfizer registered year-over-year revenue growth during the second quarter of 2024. And while the busy has been busy trimming operating expenses, it did add $1 billion to its total revenue projection for the year.
 

Top Stories

Pfizer takes $230M hit after axing failed DMD gene therapy—and tosses out RSV combo vaccine

Pfizer’s phase 3 Duchenne muscular dystrophy (DMD) gene therapy failure has blown a $230 million hole in the New York pharma's second quarter financials. The drugmaker disclosed the discontinuation of the candidate—and the financial fallout—alongside the axing of a respiratory syncytial virus (RSV) combination vaccine.

Incyte drops pair of PD-L1 drugs as part of 2nd pipeline clear-out this year

For the second quarter in a row, Incyte has used its earnings results to significantly slim down its early-stage pipeline as the Jakafi-maker channels its resources toward “high potential impact programs.”

Incyte touts 2 trial wins for PD-1 drug Zynyz, eyes comeback in anal cancer

Incyte is gunning for a first-in-class nod for its PD-1 inhibitor Zynyz in anal cancer again after being turned away by the FDA in 2021. But regulatory uncertainties remain.

Verily to relocate its HQ from San Francisco to Dallas

The Alphabet company once synonymous with Silicon Valley's penchant for moonshot startup projects, Verily will now move its South San Francisco HQ to the "business-friendly" Dallas area, after it simplified its portfolio last year.

Eli Lilly keeps up Olympics push, donating $5,000 for each Team USA milestone at Paris Games

Eli Lilly has given 24 U.S. health equity charities an extra reason to keep an eye on the 2024 Olympics and Paralympics, agreeing to donate $5,000 each time Team USA wins a medal or breaks a record.

Merck mystified by sudden 'step down' in Gardasil sales in China

On a day when Merck reported strong sales for its launch of pulmonary arterial hypertension (PAH) treatment Winrevair (sotatercept) and stalwart cancer medicine Keytruda, the positive news was overshadowed by the suddenly flat sales of Gardasil.

With BIOSECURE Act looming, WuXi AppTec shows declining revenue

With the BIOSECURE Act on the verge of passage and bringing with it the threat of crippling the business of four Chinese companies, the largest of the group, manufacturing powerhouse WuXi AppTec has reported a revenue decline. In the first half of 2024, sales for WuXi AppTec fell by 9%, to 17.2 billion yuan ($2.4 billion) year over year.

BioNTech, Regeneron rack up response rate win for mRNA cancer candidate in phase 2 trial

BioNTech has posted an early win for BNT111, linking a combination of the cancer vaccine candidate and Regeneron’s checkpoint inhibitor Libtayo to a better response rate than a historical control in melanoma patients.

Novo's GLP-1 liraglutide may protect brain from Alzheimer’s, new study finds

An old GLP-1 that has since been outshined by Ozempic may have a new path to the limelight. In a small phase 2 trial of patients with mild Alzheimer’s disease, Novo Nordisk’s liraglutide slashed cognitive decline by 18%.

Synchron links brain-computer interface with Apple Vision Pro headset

Describing the technology as a way to reconnect people with paralysis to fast-moving consumer tech, Synchron is pitching a Bluetooth standard for computer interactions that doesn't require touch or speech.

Genentech takes SMA song ‘Spaces’ to the White House for Disability Pride Month

Nearly three years after its debut, the Genentech-backed song “Spaces” made it to perhaps its biggest stage yet.
 
Fierce podcasts

Don’t miss an episode

ONC’s Micky Tripathi on creating a connected healthcare system

In this week’s episode of “Podnosis,” Micky Tripathi, Ph.D., National Coordinator for Health Information Technology at HHS, chats with Executive Editor Heather Landi about ONC’s achievements over the past 20 years, the agency’s current top priorities, the rapid adoption of AI in healthcare and more.
 

Resources

Whitepaper

Launching a Product in Europe: Understanding Supply Chain Cost Drivers

This paper explores the costs of setting up a supply chain in Europe for a new biopharma therapy. It outlines key cost drivers & the various levers decision makers can use to affect those costs.
Whitepaper

Efficient-Pro Medium and Feed 1 enable rapid and seamless upstream process development and scale-up for CHO-K1 cells

Download the white paper to learn how this innovative solution can help optimize your mAb production processes. The findings demonstrate the system's robust capability to sustain strong cell growth and high productivity, facilitating a smooth transition from laboratory to production scale.
Whitepaper

An Integrated End-to-End Approach to Antibody Drug Conjugate Development and Manufacturing

In this white paper, Lonza experts delve into the common challenges encountered by ADC developers. They explore new drug product capabilities in relation to cytotoxic drug development and manufacturing, therefore fully completing Lonza’s integrated ADC offering. Further, they discuss how this end-to-end approach can significantly accelerate the timeline to investigational new drug filing and beyond. Read this white paper to learn more.
Whitepaper

2024 Life Sciences Industry Outlook

The definitive report on the state of our industry.  Readers will gain an understanding of key indicators to monitor, future predictions, and guidance for investors and founders navigating the therapeutic enabling tools and services, healthtech and techbio sectors through 2024 and beyond.
Whitepaper

The “Best Practice Organization” & Its Importance for Success in Today’s Biopharma Industry

In a complex industry like biopharma, being a “Best Practice Organization” (BPO) is essential to success. But what is a BPO & how do you build one? This eBook provides the answers.
 

Industry Events

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

Upcoming Fierce Events

9-12
Sep
Philadelphia, PA
11
Sep
Philadelphia, PA
17-19
Sep
Virtual Event
25-26
Sep
San Diego, CA
25-27
Sep
Philadelphia, PA

View all events