Exelixis bows to Tivdak, drops ADC

Today’s Big News

Aug 7, 2024

Novo Nordisk axes once-monthly GLP-1/GIP agonist and MASH prospect


Stoke's Dravet syndrome med released from partial clinical hold as company eyes phase 3 plans


Exelixis drops tissue factor-targeting ADC after deciding it's no match for Tivdak


Relay loses interest in SHP2 inhibitor after Genentech abandons collab


Precigen laying off 20% of staff, pausing programs to eke out cash for approval filing


Elon Musk says Neuralink implanted its brain-computer chip in 2nd patient


Fierce Biotech Fundraising Tracker '24: IDRx cashes in $120M series B; Red Queen reveals $55M launch

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Thank you to Bridge Bank for sponsoring our editorial feature: Fierce 15

 
 

Featured

Fierce Biotech presents Fierce 15 at NYSE

Fierce Biotech’s Gabrielle Masson was on the New York Stock Exchange floor this morning to present the 2024 class of Fierce 15 on NYSE TV. Check out Gabrielle’s interview here and the full Fierce 15 list here!

 

Top Stories

Stoke's Dravet syndrome med released from partial clinical hold as company eyes phase 3 plans

Stoke Therapeutics’ Dravet syndrome drug has been freed from a partial hold, clearing the way for the construction of a phase 3 program.

Exelixis drops tissue factor-targeting ADC after deciding it's no match for Tivdak

Exelixis is giving up on its tissue factor-targeting antibody-drug conjugate after concluding the candidate was unlikely to best Pfizer and Genmab’s Tivdak.

Relay loses interest in SHP2 inhibitor after Genentech abandons collab

Three weeks after Roche’s Genentech unit walked away from the SHP2 inhibitor pact, Relay Therapeutics has confirmed that it won’t be pushing ahead with a solo project.

Precigen laying off 20% of staff, pausing programs to eke out cash for approval filing

Precigen is throwing everything behind a push to bring a noncancerous tumor gene therapy to market, driving it to lay off 20% of its employees and pause a raft of other programs to stretch its limited funds.

Elon Musk says Neuralink implanted its brain-computer chip in 2nd patient

Neuralink has implanted its device in a second patient, according to the startup's owner Elon Musk.

Fierce Biotech Fundraising Tracker '24: IDRx cashes in $120M series B; Red Queen reveals $55M launch

Welcome to Fierce Biotech's Fundraising Tracker, 2024's version.

Rho appoints NYU neurologist Andrew Feigin as chief medical officer

Full-service contract research organization Rho has named neurologist Andrew Feigin, M.D., its new chief medical officer. Feigin is an expert in movement disorders such as Parkinson’s disease.

Servier snags FDA approval for Voranigo, the first targeted therapy for a common type of brain tumor

Servier's Voranigo, or vorasidenib, is now the first systemic therapy for low-grade IDH-mutant brain cancer.

Novo Nordisk pulls its FDA heart failure submission for Wegovy, will reapply early next year

Novo Nordisk’s attempt to gain an approval to treat heart failure patients with its obesity drug Wegovy has been put on hold. In its quarterly earnings presentation, the Danish company said that after discussions with the FDA, it has pulled its filing and expects to resubmit in early 2025.

Amgen's marketing efforts help boost Tepezza sales

Amgen’s roller coaster ride known as Tepezza is ascending again. Is the thyroid eye disease treatment finally gaining momentum that is sustainable? In the second quarter, Tepezza generated $479 million in sales for an increase of 8% year over year and 13% sequentially. It was Tepezza’s highest quarterly sales figure since the fourth quarter of 2022.

Aeterna Zentaris not so eternal after all as biopharma rebrands to become ‘COSCIENS Biopharma’

From sounding like a companion of Thor speciality biopharma Aeterna Zentaris is no more: Meet COSCIENS Biopharma.
 
Fierce podcasts

Don’t miss an episode

New mandatory bundled payment model for hospitals

This week on “Podnosis” we're discussing a new payment model that could affect thousands of hospitals across the country. It's called TEAM, and it stands for Transforming Episode Accountability Model. It's a mandatory bundled payment program that covers five common procedures.
 

Resources

Whitepaper

Launching a Product in Europe: Understanding Supply Chain Cost Drivers

This paper explores the costs of setting up a supply chain in Europe for a new biopharma therapy. It outlines key cost drivers & the various levers decision makers can use to affect those costs.
Whitepaper

Efficient-Pro Medium and Feed 1 enable rapid and seamless upstream process development and scale-up for CHO-K1 cells

Download the white paper to learn how this innovative solution can help optimize your mAb production processes. The findings demonstrate the system's robust capability to sustain strong cell growth and high productivity, facilitating a smooth transition from laboratory to production scale.
Whitepaper

2024 Life Sciences Industry Outlook

The definitive report on the state of our industry.  Readers will gain an understanding of key indicators to monitor, future predictions, and guidance for investors and founders navigating the therapeutic enabling tools and services, healthtech and techbio sectors through 2024 and beyond.
 

Industry Events

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

Upcoming Fierce Events

9-12
Sep
Philadelphia, PA
11
Sep
Philadelphia, PA
17-19
Sep
Virtual Event
25-26
Sep
San Diego, CA
25-27
Sep
Philadelphia, PA

View all events