Zai Lab shops CD47
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Today's Rundown

Featured Story

BMS bites at GentiBio’s next-gen regulatory T cells, betting $1.9B on 3 programs

Bristol Myers Squibb is sold on GentiBio's engineered T-cell therapy, betting $1.9 billion on up to three programs. The deal comes a year after GentiBio hauled in more than $150 million in series A funds.

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Top Stories

Elevated liver enzymes force Centessa to drop a second asset in two months

Only two months after Centessa dropped its lead asset after one patient experienced elevated liver enzymes, the biotech has now culled an early-stage candidate over a similar adverse event.

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Zai Lab to shop around CD47 after deciding to ‘deprioritize’ internal development

Zai Lab has determined “due to the competitive landscape,” that internal development of monoclonal antibody ZL-1201 will be deprioritized. 

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A complex fracturing at Bone brings together inflammatory, orthopedic biotechs in reverse merger-type deal

The orthopedics-focused biotech was out looking for, well, a bone. And it found one in Medsenic, which will combine with Bone Therapeutics in an all-stock, reverse merger-type deal that will create a newly named company: BioSenic.

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Disc inks Gemini merger, secures cash from starry VC syndicate to advance ex-AbbVie, Roche drugs

Disc Medicine has secured cash to advance hematology assets picked up from AbbVie and Roche, inking a merger with the floundering Gemini Therapeutics and tapping a starry syndicate of VCs to extend its runway into 2025.

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Pursuing AbbVie and J&J, Innovent hits primary endpoint in phase 2 psoriasis trial

Innovent Biologics’ challenger to drugs including Johnson & Johnson’s Tremfya and AbbVie’s Skyrizi has cleared phase 2. The study found the anti-IL-23 monoclonal antibody, which is designed to be given less frequently than some rivals, outperformed placebo in terms of reducing psoriasis area and severity.

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Vyne to reevaluate pipeline after eczema trial fail uproots plans

Vyne Therapeutics’ lead asset has failed to improve the severity of mild-to-moderate atopic dermatitis, uprooting the biotech’s plans and sending the stock plummeting.

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Novartis’ new rare disease drug Vijoice named as an ‘empty vessel poised to be filled’

Gravity Branding chose a positive outlook when it named Novartis’ latest FDA-approved drug Vijoice but also set a deeper meaning. Vijoice “can be regarded as optimistic and life-affirming, but essentially, represents an empty vessel poised to be filled with relevant brand qualities,” the drug naming firm said.

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Walmart has a new policy denying some telehealth prescriptions for controlled drugs. It's implicating patients in recovery

Walmart is not accepting prescriptions for controlled substances written via telehealth without an in-person visit in the preceding 24 months, implicating virtual addiction treatment. Corporate policies that limit telehealth prescriptions “are a threat to patient safety and recovery,” said Anna Legreid Dopp with the American Society of Health-System Pharmacists.

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BD teams up with Labcorp to develop new companion diagnostic tests using flow cytometry

The collaboration will see the medtech giant and Labcorp’s drug development division partner up with Big Pharma companies, with the goal of offering an end-to-end solution that spans the development, approval and distribution of diagnostic tests.

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Bristol Myers, in close CAR-T race with J&J and Legend, touts Abecma win in earlier myeloma

Bristol Myers Squibb is trumpeting a first-in-class win as it tries to move Abecma up in the line of multiple myeloma treatment. But it may wind up one step behind Johnson & Johnson and Legend Biotech in terms of treatment order.

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Merck selects Saama to add machine learning tech to drug development process

Saama's Life Science Analytics Cloud is powered by cloud computing and machine learning artificial intelligence technologies, the latter of which was trained using more than 100 million clinical data points.

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Medical supplies company CCS moves into home-based diabetes care management

CCS, a company that provides medical supplies for individuals living with chronic conditions, is moving into home-based diabetes care management with coaching and monitoring services. Here's why the company's CEO believes CCS is well positioned to crack open the diabetes care market.

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Resources

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Whitepaper: End-to-end support for your asset's commercialization

The TrialCard/Triangle Insights Group platform is uniquely positioned to support you as your asset progresses through the value chain, by integrating strategic commercialization and market access insights with comprehensive patient and provider support services.

Whitepaper: Genetic Insights for Biopharmaceuticals

See how integration of innovative genetic analysis techniques into drug development is driving biopharma & biotech companies ahead.

Whitepaper: The Most Suitable Dosage Form Technologies for the Oral Delivery of Lipid-Based Formulations

What is the most suitable dosage form technology for the Oral Delivery of Lipid-Based Formulations?

Article: Formulation Strategies When Transitioning From Vial to PFS

Learn how formulation development for a PFS affects manufacturing to drive the industry toward optimizing delivery of injectable products and, ultimately, improving patient care.

Whitepaper: Catalent Pulmonary & Nasal Delivery Capabilities Sheet

Did you know Catalent has newly expanded in-house capabilities spanning clinical and commercial scale manufacturing for DPIs, unit-dose, bi-dose and preserved multi-dose nasal sprays?

Whitepaper: Intranasal Drug Product Development: Formulation to Manufacturing

What are key considerations for intranasal delivery in the treatment of acute and chronic conditions?

Case Study: Versatility of Softgel Technology - Encapsulation of a Volatile Compound

Learn more about how the versatility of Softgel Technology helped a customer with a volatile compound.

Article: Lipid-Based Drug Delivery System to Bring Poorly Soluble Drugs to Market

How can Lipid-Based Drug Delivery System help bring poorly soluble drugs to market?

eBook: Orally Inhaled & Nasal Drug Delivery: A Pipeline of Opportunities

Carla Vozone discusses the significant trends in the OINDP segment including large molecules and novel indications, changes within CDMOs and various challenges facing the industry.

On-Demand Webinar: The Faster Path From Pre-Filled Syringe to Auto-Injector

Ypsomed and Catalent Biologics experts discuss strategies for integrated PFS manufacturing and auto-injector assembly to accelerate timelines and more in this webinar.

Events