Pyxis, Atai tidy up pipelines
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Today's Rundown

Featured Story

Biotechs face brutal pipeline decisions as industry waits for M&A 'buffet'

We’re seeing a seemingly unprecedented reckoning from biotech C-suites, where executives are making tough calls about continuing to keep the lights on or cutting once-promising candidates.

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Top Stories

GSK turns down one solid tumor collaboration, but Ideaya thinks it’s for the best

GSK has passed on the chance to go all-in on one of its cancer collaborations with Ideaya Biosciences, but the precision medicine company feels fine about the decision.

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Pyxis puts 2 drugs on backburner and a 3rd on the scrapheap to rally resources behind lead cancer programs

Pyxis Oncology is slimming down after a tough start to life on public markets, pausing work on two assets and stopping development of a third altogether to focus its cash on getting its lead programs to clinical data drops.

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Atai says goodbye to pipeline prospects, slimming down and taking on debt to extend cash runway

Atai Life Sciences is among the better-capitalized biotechs, ending June with $312 million left over from its private rounds and IPO. But the mental health player has still joined the growing list of companies that are trimming their pipelines and taking on debt to keep priority programs moving forward

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Clene claims MS drug win, but COVID disruption masks some tricky data

Clene Nanomedicine has chalked up a win for its gold nanocrystal suspension to treat multiple sclerosis—although it looks like the COVID-19 pandemic may have lent a helping hand.

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Checkpoint calls it quits on cancer drug trial, citing enrollment problems stemming from war in Ukraine

Checkpoint is calling it quits on a phase 3 combo trial of its lead cancer med because of the ongoing war in Ukraine. The company had the majority of its trial sites in Russia and says it's dealt with a "substantially longer" enrollment period than expected.

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Time may be running out for anti-aging biotech AgeX as funds dry up

AgeX Therapeutics, a preclinical biotech looking to turn back the clock on aging, may have to wind down, announcing “substantial doubt” about its ability to continue as money runs dry and debts mount.

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Democrats' drug pricing reforms may not be so bad for pharma, analysts say

After clearing the Senate early last week, the Democrats’ Inflation Reduction Act bill has made its way through the U.S. House of Representatives, paving the way for Medicare to bargain for drug prices, cap out-of-pocket costs for seniors and more. Despite the fierce resistance from the drug industry, analysts say the bill won't be so bad for biopharma players.

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Boston Scientific bulks up blood-blocking portfolio with Obsidio acquisition

After a whirlwind 2021 that saw Boston Scientific gobbling up a handful of smaller companies left and right, the medtech giant’s M&A appetite seems to have slowed.

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With Pfizer, AZ and Merck leading the way, Big Pharma weathered the economic storm in Q2

Despite a bevy of economic challenges in the second quarter, the biopharmaceutical industry got through the period with solid sales as 15 of the top 24 companies saw a revenue increase over the second quarter of 2021. Pfizer, AstraZeneca and Merck were the top gainers while Regeneron and BioNTech took the largest hits.

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Health tech Q2 earnings update—GoodRx resolves grocer spat; Progyny sees strong demand for fertility benefits

Digital healthcare platform GoodRx had good news to share during its second-quarter earnings call as it settled a costly spat with a grocery chain's drug store and posted financial results that beat Wall Street forecasts.

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Illumina sets aside $453M to prep for potential EU fines over Grail acquisition

The rainy day money for potential legal troubles dragged Illumina's quarterly income into the red, while sales slumped due to global macroeconomic challenges and the company cut back its financial outlook for the year.

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Carla Vozone discusses the significant trends in the OINDP segment including large molecules and novel indications, changes within CDMOs and various challenges facing the industry.

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