Turnstone narrows cancer cell therapy focus

Today’s Big News

Aug 15, 2024

IRA negotiations slash Medicare prices for Big Pharma blockbusters by up to 79%


Using AI and brain implants, researchers reconnect ALS patient with their lost voice


Turnstone narrows cell therapy focus to 'high unmet need' tumor indications


US court rules for AstraZeneca, erasing Pfizer's $107.5M jury award in patent infringement case


'We're firing on all cylinders': Bayer pharma BD chief says group overhaul not slowing dealmaking


As mpox outbreak spreads across Africa, Siga's antiviral Tpoxx misses the bar in Congo study

 

Featured

IRA negotiations slash Medicare prices for Big Pharma blockbusters by up to 79%

The White House has revealed significantly reduced prices for 10 prescription drugs affected by the first wave of Medicare negotiations mandated by the Inflation Reduction Act, the Biden administration initiative which includes several measures designed to lower the cost of healthcare in the U.S.
 

Top Stories

Using AI and brain implants, researchers reconnect ALS patient with their lost voice

Using sensors developed by Blackrock Neurotech and AI text-to-speech software that sounds like his own voice, 45-year-old Casey Harrell was able to say, “It feels a lot like me."

Turnstone narrows cell therapy focus to 'high unmet need' tumor indications

Turnstone Biologics is narrowing the focus of phase 1 trials of its lead tumor-infiltrating lymphocyte, with cutaneous melanoma and breast cancer no longer in the mix.

US court rules for AstraZeneca, erasing Pfizer's $107.5M jury award in patent infringement case

Less than three months after a Delaware federal jury ordered AstraZeneca to pay $107.5 million to Pfizer in a patent infringement case, a Delaware judge has nullified the award and invalidated the patents behind the original lawsuit.

'We are firing on all cylinders': Bayer pharma BD chief says group overhaul not slowing dealmaking

To Juergen Eckhardt, M.D., who leads both the investment arm Leaps by Bayer and the pharma business development team, the ongoing overhaul won’t disrupt the German company’s dealmaking appetite.

As mpox outbreak spreads across Africa, Siga's antiviral Tpoxx misses the bar in Congo study

Despite missing the trial's primary endpoint of time to lesion resolution, the study suggested that the treatment may be most beneficial for those treated early and those with severe disease.

Incyte, Syndax bag FDA approval for potential blockbuster Niktimvo in graft-versus-host disease

Incyte has expanded its graft-versus-host disease offerings beyond Jakafi. The new addition comes from Syndax Pharma-partnered axatilimab, which received FDA approval as a third-line therapy.

In the wake of Céline Dion's diagnosis and comeback, stiff-person syndrome researchers and advocates march toward a cure

Céline Dion stands alone as a singer, a chart-topping ballad-belter who recorded some of the most iconic songs of all time, including “My Heart Will Go On” from the "Titanic" soundtrack. But, in 2022, Dion made headlines not for her one-in-a-million voice, but for a one-in-a-million diagnosis: a rare neurological disease called stiff-person syndrome.

Tarsus 'firing on all cylinders' as Xdemvy launch, sales force expansion roll ahead: CEO

Roughly one year since the commercial rollout of Tarsus Pharmaceuticals’ first marketed product Xdemvy, the company is touting the medicine’s debut as “one of the most successful eye care launches to date.”

HistoSonics nets $102M to boost its sound beam-powered liver cancer therapy

The Edison system uses vibrations from sound waves to create bubbles of gas within a tumor, with enough energy to destroy the targeted tissue.

After clearing out heart disease drug, Arrowhead maps out obesity development plans

After Arrowhead cleared out work on a clinical-stage cardiovascular candidate, the company is filling the blank space with two obesity assets, both slated to enter the clinic in early 2025.

ArriVent licenses ADC from $100M biobuck deal with Aarvik

Two and half years after it signed a $100 million biobucks deal with Aarvik Therapeutics to work on an undisclosed “novel oncology drug,” ArriVent BioPharma has decided to license the candidate—and confirmed that it’s an antibody-drug conjugate.
 
Fierce podcasts

Don’t miss an episode

What the data says about the telehealth market

In this week's episode of "Podnosis," we’re discussing the challenges and opportunities for telehealth, given some notable setbacks for the industry in recent months.
 

Resources

Whitepaper

Launching a Product in Europe: Understanding Supply Chain Cost Drivers

This paper explores the costs of setting up a supply chain in Europe for a new biopharma therapy. It outlines key cost drivers & the various levers decision makers can use to affect those costs.
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Efficient-Pro Medium and Feed 1 enable rapid and seamless upstream process development and scale-up for CHO-K1 cells

Download the white paper to learn how this innovative solution can help optimize your mAb production processes. The findings demonstrate the system's robust capability to sustain strong cell growth and high productivity, facilitating a smooth transition from laboratory to production scale.
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2024 Life Sciences Industry Outlook

The definitive report on the state of our industry.  Readers will gain an understanding of key indicators to monitor, future predictions, and guidance for investors and founders navigating the therapeutic enabling tools and services, healthtech and techbio sectors through 2024 and beyond.
 

Industry Events

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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