Pfizer, BioNTech’s combo shot fails to tame influenza B

Today’s Big News

Aug 16, 2024

Genentech to shut down cancer immunology department amid broader R&D rethink


Following rejection and retractions, Lykos caps off chaotic week by cutting 75% of staff 


Pfizer, BioNTech's combo mRNA shot is latest to be defeated by influenza strain B 


'We are firing on all cylinders': Bayer pharma BD chief says group overhaul not slowing dealmaking 


In the wake of Céline Dion's diagnosis and comeback, stiff-person syndrome researchers and advocates march toward a cure 


Chutes & Ladders—CRISPR-focused Caribou christens new CMO 

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

Genentech to shut down cancer immunology department amid broader R&D rethink

Genentech will close its cancer immunology department to form a single oncology research organization. Unit head and renowned cell biologist Ira Mellman, who has been with the company for 17 years, will depart in the coming months.
 

Top Stories

Following rejection and retractions, Lykos caps off chaotic week by cutting 75% of staff

Lykos Therapeutics is capping off an awful week with a massive reorganization, laying off about 75% of staff in the aftermath of an FDA rejection and the retraction of three research papers on the biotech’s MDMA treatment due to protocol violations at a clinical trial site.

Pfizer, BioNTech's combo mRNA shot is latest to be defeated by influenza strain B

Pfizer and BioNTech may have a strong pedigree in the mRNA vaccine game, but, when it comes to flu, they’ve run up against the same problem as their peers—neutralizing influenza strain B.

'We are firing on all cylinders': Bayer pharma BD chief says group overhaul not slowing dealmaking

To Juergen Eckhardt, M.D., who leads both the investment arm Leaps by Bayer and the pharma business development team, the ongoing overhaul won’t disrupt the German company’s dealmaking appetite.

In the wake of Céline Dion's diagnosis and comeback, stiff-person syndrome researchers and advocates march toward a cure

Céline Dion stands alone as a singer, a chart-topping ballad-belter who recorded some of the most iconic songs of all time, including “My Heart Will Go On” from the "Titanic" soundtrack. But, in 2022, Dion made headlines not for her one-in-a-million voice, but for a one-in-a-million diagnosis: a rare neurological disease called stiff-person syndrome.

Chutes & Ladders—CRISPR-focused Caribou christens new CMO

Tina Albertson, M.D., Ph.D., is taking over the top doctor spot at CRISPR-focused Caribou Biosciences.

HistoSonics nets $102M to boost its sound beam-powered liver cancer therapy

The Edison system uses vibrations from sound waves to create bubbles of gas within a tumor, with enough energy to destroy the targeted tissue.

Blackstone to buy majority stake in Chartis from Audax Private Equity

The Chicago-based healthcare advisory firm announced Wednesday that it had entered into a definitive agreement to receive a majority investment from funds managed by Blackstone.

Fierce Pharma Asia—Merck-Curon bispecific deal; Legend's path forward; Missing adverse events in Amgen FDA filing

Merck licensed a bispecific from a Chinese biotech with plans to target oncology and autoimmune diseases. Legend Biotech is taking a close at its business as M&A has emerged as an option. A large number of missing adverse events in South Korea triggered a full-scale check-up during the FDA's review of Amgen's Imdelltra. And more.
 
Fierce podcasts

Don’t miss an episode

The TROP2 race for supremacy

In this week’s episode of “The Top Line,” Fierce executive editor Eric Sagonowsky chats with Angus Liu about his feature story on the three TROP2 front-runners.
 

Resources

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2024 Life Sciences Industry Outlook

The definitive report on the state of our industry.  Readers will gain an understanding of key indicators to monitor, future predictions, and guidance for investors and founders navigating the therapeutic enabling tools and services, healthtech and techbio sectors through 2024 and beyond.
 

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On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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