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August 21, 2019___

Today's Rundown

Featured Story

NuCana's retooled chemo drug comes up short in pancreatic cancer phase 3

A phase 3 study of NuCana’s lead drug, a reformulated version of Eli Lilly’s Gemzar, was halted because it is unlikely to succeed. A data-monitoring committee decided it was doubtful the new version would beat the chemotherapy veteran.

Top Stories

Chasing Astellas and Mitsubishi, GSK files for Japanese approval of oral anemia drug

GlaxoSmithKline has filed for approval of renal anemia drug daprodustat in Japan. The filing follows data from Japanese phase 3 trials that assessed the oral hypoxia-inducible factor prolyl hydroxylase inhibitor in chronic kidney disease patients.

Oncorus raises $80M for 2-front oncolytic virus R&D push

Oncorus has raised $79.5 million to advance oncolytic viruses. The series B round equips Oncorus to move its lead prospect into the clinic and nominate an intravenously administered viral candidate early next year.

Y Combinator startup pursuing 'scarless' pouch for cell transplants in diabetes

Encellin is working on a cell pouch that cuts down on the disruptive scarring that comes with encapsulated cell transplants and eliminates the need for anti-rejection drugs. It hopes to test an insulin-producing cell transplant in humans next year.

Pfizer adds $500M to gene therapy manufacturing plant where it will hire 300 workers

Pfizer is running behind in the race for a gene therapy and is shifting its production efforts into overdrive. The company will inject another $500 million into a gene therapy manufacturing plant and says it will hire another 300 workers.

Resources

[Article] Sales Compensation: 7 Trending Topics

From sales headcount and budgets to new product launches and saying “yes” to millennials, hear the top 7 topics that are trending in sales compensation.

[Whitepaper] Enhancing Productivity in Drug Discovery: Removing Inefficiencies and Distractions Caused by Chemicals and Biologics Management

The regulations and managing processes for hazardous, controlled and rare chemicals and biologics necessary for drug discovery are a huge distraction for R&D labs. Learn from the perspectives of industry executives the pain points and improvements they want in their processes for chemicals and biologics in pharmaceuticals R&D.

[Whitepaper] The Supply Chain Planning Cure for Everything from Product Expirations to Patent Cliffs

Download this life sciences industry spotlight to discover how concurrent planning can help you overcome complex supply chain challenges to drive down costs and improve efficiency.

[Whitepaper] Flow Chemistry: A Scale-up Solution for Modern API Development and Manufacturing

Patheon, part of Thermo Fisher Scientific, offers advanced API manufacturing technologies such as continuous processing and continuous analytics to deliver high-quality products with well-defined features to meet your timelines and volume requirements.

[Whitepaper] The Impact of Artificial Intelligence on Outcomes Based Contracting

Understanding the challenges for formulary decision makers and manufacturers.

[Whitepaper] How Vertex Cut Database Build Timelines by 50%

This white paper details how leveraging new reporting capabilities, live UAT feedback sessions, and an agile design approach to study builds will save them time and money.

[Whitepaper] The Truth about Physician Referrals and Clinical Trials

The Study Voices survey challenges the myth that physicians won’t refer patients to clinical trials, and it identifies opportunities to engage physicians as partners in the enrollment process.

[Case Study] Clinical Supply Management

Download the case study to learn about the clinical supply management tools that helped a small sized pharma company during phase III of a multi-arm oncology study.

[Video] Demand Led Services and Clinical Supply Efficiency

Watch a short video on demand led supply model. It is designed to meet the needs of patients, clinical sites, clinical team and sponsors and results in shorter lead time, less waste, less stock out risk and no booklet labels.

[eBook] Strategies for Efficient Clinical Supply Management and Forecasting

Download the eBook to explore a proactive approach for clinical supply management.

Events