Genentech axes 93 roles amid restructure

 

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Today’s Big News

Aug 28, 2024

Bayer pens $547M biobucks pact with biotech pushing the boundaries of noncoding RNA


Neurocrine’s KarXT rival hits in phase 2 schizophrenia trial—but only at lowest dose


Genentech telegraphs 93 layoffs in California after sharing plans to shutter cancer immunology research unit


After obesity, Pfizer and Flagship pick 2 more targets for multibillion-dollar partnership 


UCLA scoops $120M gift for immunology and immunotherapy site, plans vaccine development group 

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

Bayer pens $547M biobucks pact with biotech pushing the boundaries of noncoding RNA

The company has signed a deal worth over half a billion biobucks to partner up on two programs with NextRNA Therapeutics.
 

Top Stories

Neurocrine’s KarXT rival hits in phase 2 schizophrenia trial—but only at lowest dose

Neurocrine Biosciences has achieved its hoped-for profile in a phase 2 schizophrenia trial, delivering its targeted level of efficacy with a lower rate of gastrointestinal adverse events than Bristol Myers Squibb’s KarXT. But the biotech only saw efficacy at the lowest dose—the three higher doses all failed.

Genentech telegraphs 93 layoffs in California after sharing plans to shutter cancer immunology research unit

Genentech will lay off 93 employees in South San Francisco starting in early October, the company confirmed through a Worker Adjustment and Retraining Notification alert sent to California. While it isn’t immediately clear what types of roles will be affected, local news outlet SFGate said the job cuts would impact scientists, engineers, managers and analysts, plus one executive.

The Evolving Alzheimer’s Disease Landscape

New disease-modifying drugs, biological pathways and blood-based biomarker tests are among the rapid changes shaping the Alzheimer’s disease landscape

After obesity, Pfizer and Flagship pick 2 more targets for multibillion-dollar partnership

Flagship Pioneering and Pfizer have added Quotient into their 10-program partnership, inking a deal to discover new targets for two programs in cardiovascular and renal diseases.

The Crucial Role of HEK293 DNA Quantification in Biotherapeutics

In this episode of The Top Line, sponsored by Bio-Rad, Dipika Gurnani delves into the challenges and solutions of quantifying HEK293 DNA in biotherapeutics, a field revolutionizing healthcare for over 350 million patients worldwide.

UCLA scoops $120M gift for immunology and immunotherapy site, plans vaccine development group

UCLA has received a $120 million commitment to support the recently established California Institute for Immunology and Immunotherapy, positioning the university to establish research entities in Los Angeles focused on vaccine development and the microbiome.

Novartis taps Lindy to turn biologic drugs into at-home injectables, puts nearly $1B on the line

Novartis has formed a strategic collaboration with drug delivery specialist Lindy Biosciences to develop self-administered versions of the Swiss pharma’s innovative drugs.

Eli Lilly rolls out direct patient access to weight loss star Zepbound—at a deep discount

Eli Lilly is offering its popular weight-loss drug Zepbound directly to consumers at a discount through its own online pharmacy. The company hopes the move could expand access while addressing other issues such as high prices and off-label cosmetic usage.

Following growth, Curi Bio expands into larger Seattle lab space

Curi Bio is on the move. The Seattle-based companu has signed a seven-year lease for a roomy, 13,942-square-foot space, with plans to move in by early 2025.

In key win for GSK, Delaware court will review decision to allow expert testimony in Zantac cases

The Delaware Supreme Court has upheld a GSK appeal, deciding to review the state’s Superior Court decision to allow expert testimony that would support 75,000 personal injury Zantac lawsuits that have been consolidated in the state.
 
Fierce podcasts

Don’t miss an episode

What Chevron’s overturn means for biopharma

This week on "The Top Line," we look at the potential effects of the Chevron overturn on the biopharma industry.
 

Resources

Whitepaper

Epilepsy Clinical Trials

Finding an effective epilepsy treatment can be arduous. Download this brochure to delve into how IQVIA's expertise and innovative strategic approach can streamline the clinical trial process, helping to get new therapies to patients who need them sooner.
Whitepaper

Launching a Product in Europe: Understanding Supply Chain Cost Drivers

This paper explores the costs of setting up a supply chain in Europe for a new biopharma therapy. It outlines key cost drivers & the various levers decision makers can use to affect those costs.
 

Industry Events

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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