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Today's Rundown

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Pfizer CEO says coronavirus vaccine data will roll in fast enough for results late October

Pfizer CEO Albert Bourla said the company has enrolled about 23,000 people for its phase 3 COVID-19 vaccine trial, and the way things are going, initial results should be ready in late October. If the numbers are positive, the company would be ready to ask FDA for an authorization immediately.

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Top Stories

20% of clinicians considering leaving primary care in light of COVID-19-linked financial challenges: survey

The primary care industry is contracting in the face of financial challenges from the COVID-19 pandemic, according to a new survey from the Larry A. Green Center and Primary Care Collaborative.

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Sanofi, GSK start COVID-19 vaccine trial, eye H1 2021 approval

Sanofi and GlaxoSmithKline have moved their adjuvanted protein-based COVID-19 vaccine into the clinic, setting them on a path they expect to lead to a filing for approval in the first half of next year.

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Steroids can save the lives of very ill COVID-19 patients, new studies confirm

When researchers in the U.K. said in June that the low-cost corticosteroid dexamethasone could reduce death rates in critically ill COVID-19 patients, clinicians still had doubts about whether to change their treatment practice without full data. But a new meta-analysis examining clinical trials in different parts of the world, whose findings were simultaneously published on Wednesday in JAMA, will likely change that.

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Biopharma roundup: U.S. won’t join WHO global vaccine initiative

Albany Molecular will perform fill-finish work on "millions" of AstraZeneca shots. The NIH selected nine more test makers to advance through its COVID diagnostics competition. The U.S. won't join WHO's COVAX, a White House spokesperson said. California could make its own generic drugs, plus many U.S. hospitals are hesitant to treat COVID patients with plasma.

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Bloomberg commits $100M to historically Black medical schools amid COVID-19 pressures

The funds from Bloomberg Philanthropies will go toward "significantly reducing the debt burden" of about 800 students, many who are experiencing increased financial pressure amid COVID-19. 

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NIH's COVID-19 diagnostic competition awards $129M to boost 9 more test makers

The National Institutes of Health has picked nine additional test manufacturers to advance through its “Shark Tank”-like COVID-19 diagnostics competition—alongside $129.3 million in new funding to help scale up the production of both point-of-care screening tests and high-throughput laboratory assays.

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Biotech CEOs pen standards for coronavirus trials, data disclosures amid FDA reputation crisis

Amid doubts about the FDA’s decision-making process during the pandemic, biotech CEOs on the front lines of research are laying out their approach and asking “all parties” involved in the process to adhere to high scientific standards. 

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MedPAC: For-profit systems fare better than non-profits in weathering COVID-19 cash crisis

A new analysis from MedPAC found for-profit hospital systems have done a better job of weathering the COVID-19 financial crisis than their non-profit counterparts.

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AstraZeneca signs on Albany Molecular to help boost COVID-19 shot production

British drugmaker AstraZeneca is on a mission to lock in as many manufacturing partners as possible to support a planned global rollout for its COVID-19 vaccine frontrunner. A New York CDMO has now jumped on board, and it will commit its Southwestern facility to help pick up the slack.

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