10 highest value R&D projects

Today’s Big News

Sep 5, 2023

Illumina nets new CEO with Agilent life sciences leader 


Novartis files suit against IRA after blockbuster Entresto makes CMS' price negotiations list  


The 10 highest value R&D projects in biopharma  


Investors shower Star Therapeutics with $90M for constellation of biotechs, antibody therapies 


Amgen tipped to keep Otezla market share in fight with BMS' Sotyktu, leaving opportunity for J&J  

 

Featured

Illumina nets new CEO with Agilent life sciences leader

Jacob Thaysen will make the jump after serving as Agilent Technologies' president of life sciences and applied markets. He will take the top job at Illumina Sept. 25.
11-14
Sep
Philadelphia, PA
 

Top Stories

Novartis files suit against IRA after blockbuster Entresto makes CMS' price negotiations list

Add Novartis to the list of biopharma giants that have filed lawsuits against the U.S. government as a reaction to the Inflation Reduction Act. The case was filed Friday in New Jersey federal court, three days after the CMS revealed that Novartis’ heart failure treatment Entresto was among 10 drugs subject to price negotiations in 2026.

The 10 highest value R&D projects in biopharma

The world’s pharmaceutical companies are set to invest $302 billion in R&D by 2028—but what will they get in return? Fierce Biotech explores the 10 therapies with the highest potential value.

Investors shower Star Therapeutics with $90M for constellation of biotechs, antibody therapies

The latest financing will in part go toward VGA039, an early-stage mAB being developed by Star's offshoot Vega to treat von Willebrand disease.

Amgen tipped to keep Otezla market share in fight with BMS' Sotyktu, leaving opportunity for J&J

Amgen’s $13.4 billion Otezla bet can withstand competition from Bristol Myers Squibb’s Sotyktu. That is the conclusion of analysts at Spherix Global Insights, who found Amgen is holding on to its market share and largely limiting BMS’ growth to the conversion of users of injectable biologics.

Revvity revamps imaging offerings with launch of 4 high-throughput scanners

When PerkinElmer’s diagnostics and life sciences businesses rebranded as Revvity earlier this year, the company told Fierce Medtech that the newly streamlined structure would allow them “to get more products to the market in a much faster way.”

Seagen, Genmab's Tivdak improves survival for cervical cancer patients in phase 3 trial

The drug boosted overall survival, progression-free survival and objective response rates in patients with recurrent or metastatic cervical cancer who had disease progression on or after a front-line therapy.

BMS hands Zenas a quick win, paying $50M for regional rights to ex-Xencor autoimmune drug

Zenas BioPharma has flipped regional rights to its bifunctional monoclonal antibody obexelimab. Bristol Myers Squibb has taken the other side of the deal, paying $50 million upfront for certain Asian rights to an asset that Zenas picked up from Xencor in return for a stake in its business less than two years ago.

Amber Therapeutics acquires neurostim implant at the heart of its urinary incontinence therapy

Two years after spinning out of the University of Oxford, Amber Therapeutics is now the proud owner of the technology that serves as the basis for its neuromodulation system.

Years after $2B buyout, Nestlé ditches Aimmune's peanut allergy drug Palforzia

After lackluster sales dampened the initial enthusiasm that came with a $2.1 billion acquisition, Nestlé has finally found a new owner for its peanut allergy drug Palforzia.

Tonix's long COVID drug fails phase 2 trial in pain, but biotech holds out hope for fatigue

Tonix Pharmaceuticals says its fibromyalgia treatment turned long COVID med failed to improve severe pain in patients with the post-COVID condition. However, some potential improvements in measurements of fatigue and sleep quality are guiding the company toward a new focus.

Fierce 50 spotlight: Breakthroughs category chair Eric Sagonowsky

The Breakthroughs category of the Fierce 50 features those who have made groundbreaking discoveries that have significantly advanced medical science and transformed patient care.
 

Resources

Whitepaper

What Are the Benefits of Generative AI for Pharma?

From trial site feasibility and patient populations to data analysis, generative AI has the potential to revolutionize drug discovery and clinical trial recruitment at both the therapeutic area and indication level.
Whitepaper

Discovering High-Affinity, Functional Anti-GLP-1R Antibodies

Learn how a GPCR-focused library with a cell-based biopanning strategy led to the discovery of 13 high-affinity and selective anti-GLP-1R antibodies with highly developable therapeutic properties.
Whitepaper

Five ways to get the most from your lab and manufacturing facilities

Learn more about how you can improve the productivity of your research and manufacturing operations and accelerate the journey from laboratory to saving lives.
Whitepaper

Transitioning from using RUO to cGMP chemicals for clinical trials

By 2030, the global demand for biologics is projected to grow at a CAGR of 8.7% and the challenges, risks, and costs of bringing large molecule products to market are growing exponentially.
Whitepaper

Biotech in the UK: Mapping the Runway to Success

15 biotech executives from the Cambridge area discuss the current biotech landscape, as well as challenges, opportunities, and best practices for emerging biotech companies seeking success in the UK and beyond.
Whitepaper

Plan for success with your process liquid and buffer preparation

Learn how process liquids and buffers impact your total cost of ownership (TCO) and how outsourcing can revolutionize your approach, ensuring quality standards and improving productivity.
 

Industry Events

The MedTech Conference

The MedTech Conference

 

Upcoming Fierce Events

11-14
Sep
Philadelphia, PA
13
Sep
Philadelphia, PA
19-21
Sep
Virtual Event
26-28
Sep
Philadelphia, PA
5-6
Oct
San Diego, CA

View all events