Plus our top stories of the week

This Week

Sep 6, 2024

ArsenalBio raises $325M for solid tumor CAR-T science with Regeneron and BMS in tow


Alnylam's Amvuttra turns in 'grand slam' showing in ATTR-CM, but leaves a window open for rivals


Sanofi's tolebrutinib fails 2 of trio of phase 3 MS trials, but pharma still plans FDA filing


Novo rekindles heart failure hopes for semaglutide with new pooled analysis


3 execs resign as Dyne posts mixed data for DMD candidate 


Astellas Gene Therapies to turn out the lights at South San Francisco production plant 


ESC 2024: Abbott MitraClip study shows gains in functional-yet-leaky heart valves 

 

Featured

ArsenalBio raises $325M for solid tumor CAR-T science with Regeneron and BMS in tow

Arsenal Biosciences is moving on up. The cell therapy company has added on $325 million in ammunition with big-name backers like Regeneron joining the artillery.
 

Top Stories

Alnylam's Amvuttra turns in 'grand slam' showing in ATTR-CM, but leaves a window open for rivals

At the European Society of Cardiology conference in London, Alnylam presented positive data from the phase 3 HELIOS-B trial which assessed RNA silencer Amvuttra (vutrisiran) as a treatment for transthyretin amyloid cardiomyopathy (ATTR-CM).

Sanofi's tolebrutinib fails 2 of trio of phase 3 MS trials, but pharma still plans FDA filing

Sanofi is still set on taking its multiple sclerosis med tolebrutinib drug to the FDA, executives have told Fierce Biotech, despite the BTK inhibitor falling short in two of three phase 3 trials that read out on Monday.

Novo rekindles heart failure hopes for semaglutide with new pooled analysis

Novo’s semaglutide cut the risk of combined cardiovascular death or worsening heart failure events by 31%, based on an incident rate of 5.4% in semaglutide patients versus 7.5% in those on placebo, the company said Friday. Semaglutide also led to a 41% lower risk of worsening HF, according to a pooled analysis of four Novo Nordisk trials.

3 execs resign as Dyne posts mixed data for DMD candidate

In tandem with a data drop on its Duchenne muscular dystrophy candidate in patients suited to exon 51 skipping therapy, Dyne Therapeutics has announced a slew of executive changes, including multiple appointments and departures.

Astellas Gene Therapies to turn out the lights at South San Francisco production plant

Several months after its parent company unveiled new labs and office space to unite cell and gene therapy research on the West Coast, Astellas Gene Therapies is turning out the lights at a California production plant.

ESC: Abbott MitraClip study shows gains in functional-yet-leaky heart valves

The trial’s long-awaited results were once expected to settle some of the differences between two previous examinations of the company’s MitraClip approach.

Radiotherapy leader Novartis brings US isotope production in house, builds West Coast plant

Novartis is further bolstering its radiotherapy infrastructure with a brand-new facility and the expansion of an existing site that will bring critical production of radioactive isotopes in house in the U.S.

National Science Foundation grants $22M to form a research hub for extreme microbes

Many microbes are extremophiles, capable of surviving conditions that would spell instant death for you and me. From deep-sea hydrothermal vents to boiling hot springs, these single-celled creatures have evolved special tools to help them thrive in tough places. Researchers have long wanted to harness these tools for human applications.

Takeda taps longtime FleishmanHillard alum to head up global corporate brand and content

A new appointee with more than two decades of comms experience will soon take the reins of Takeda’s worldwide brand strategy.
 
Fierce podcasts

Don’t miss an episode

Minimizing plastics use and risk in healthcare 

In this week's episode of "Podnosis," two experts break down the history of plastics use in the healthcare sector and what it would take for an organization to phase them out.
 

Resources

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Unlock the future of biopharma cold chain

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Navigating the Drug Supply Chain Security Act (DSCSA): A Guide to Ensuring Compliance

DSCSA Compliance with a Trusted Partner
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Building a “Best Practice” Commercial Organization in Biopharma

We interviewed dozens of biopharma leaders on the critical success factors for building a Best Practice commercial organization. This report shares what we learned.
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Epilepsy Clinical Trials

Finding an effective epilepsy treatment can be arduous. Download this brochure to delve into how IQVIA's expertise and innovative strategic approach can streamline the clinical trial process, helping to get new therapies to patients who need them sooner.
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Enhance the patient experience leveraging AI

Start leveraging AI to enhance the patient experience while improving personalization, navigation and adherence with the latest free eBook by RxPx.
 

Industry Events

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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