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September 07, 2017

Today's Rundown

  1. GlaxoSmithKline hits ‘go’ on Adaptimmune’s SPEAR T-cell program

  2. Alnylam halts fitusiran trials after patient with hemophilia dies

  3. Lilly to shutter U.S., China R&D centers

  4. AstraZeneca and Amgen severe asthma drug is 'one to watch' after phase 2 win

  5. Cancer upstart Gritstone gains major $93M series B

  6. Verona COPD drug beats Boehringer blockbuster in phase 2

Featured Story

GlaxoSmithKline hits ‘go’ on Adaptimmune’s SPEAR T-cell program

As CAR-T and T-cell therapies continue to make headlines, GlaxoSmithKline has taken up the option to work on Adaptimmune’s T-cell therapy.

Top Stories

Alnylam halts fitusiran trials after patient with hemophilia dies

Alnylam has suspended dosing in trials of RNAi drug fitusiran after a patient with hemophilia A died in one of the studies. The biotech is now developing a strategy to mitigate the risk of more patients suffering fatal blood clots before resuming the trials.

Lilly to shutter U.S., China R&D centers

As part of a major series of global cuts across its divisions, Eli Lilly is putting two research centers on the chopping block.

AstraZeneca and Amgen severe asthma drug is 'one to watch' after phase 2 win

A first-in-class therapy developed by AstraZeneca and Amgen looks like a strong treatment candidate for severe uncontrolled asthma, according to a respiratory specialist.

Cancer upstart Gritstone gains major $93M series B

After getting off a $102 million series A, Gritstone Oncology has followed up with an impressive $92.7 million second round.

Verona COPD drug beats Boehringer blockbuster in phase 2

Verona Pharma has released results showing that adding its RPL554 to Boehringer Ingelheim’s Spiriva improves lung function in chronic obstructive pulmonary disease (COPD) patients. Data from the small phase 2a trial suggest Verona’s PDE3/PDE4 inhibitor may complement long-acting muscarinic antagonist bronchodilators such as Spiriva.

Resources

[Whitepaper] Modernizing the Patient Journey

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[Webinar] Five ways to make your patient support program a success

Join this webinar to learn how to design, deliver, and measure a successful patient support program. Presented by Nareda Mills, Ashfield's SVP of Patient Services in the US, you’ll discover how to improve adherence and improve patient outcomes using 5 key methods.

[Whitepaper] The Impact of Contraceptive Requirements on Pediatric Clinical Trials

Children participating in pediatric clinical trials are included in the contraceptive requirements applied to women of child-bearing potential, creating significant challenges for sponsors, parents, investigators and study staff.

[Webinar] Within-Subject Clinical Trials: Intro to New Methods & Stat. Models

In this webinar, we will introduce the rapidly-evolving within-subject clinical trial (WSCT) methods for early phase evidence generation that require fewer people, less time, and usually less funding than traditional early phase methods.

Events

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