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This Week

Sep 15, 2023

Novo, Lilly set to dominate $71B GLP-1 drug market by 2032: J.P. Morgan


Roche places 'stronger gates' on phase 3 pipeline to reduce failure rate


In warning letters, FDA tells 8 companies to stop selling illicit eye drugs


After initial stumbles, Moderna finally gains clean phase 3 win for mRNA flu shot


Moderna follows AstraZeneca's lead, dumping 2 previously shared programs—plus 2 more


AbbVie's Skyrizi deals heavy blow to J&J's Stelara in head-to-head Crohn's disease study

 

Featured

Novo, Lilly set to dominate $71B GLP-1 drug market by 2032: J.P. Morgan

Promising heart data for Novo Nordisk's Wegovy are a "paradigm shift," according to J.P. Morgan, which has doubled its market projection for GLP-1 diabetes and obesity treatments to $71 billion for 2032. The analysts project Novo and Eli Lilly will dominate the market.
 

Top Stories

Roche places 'stronger gates' on phase 3 pipeline to reduce failure rate

Roche has installed “stronger gates” to ensure that drug candidates only make it into phase 3 trials if they have a high chance of success, CEO Thomas Schinecker has revealed.

In warning letters, FDA tells 8 companies to stop selling illicit eye drugs

The companies included in the warning letter sweep are: Boiron, CVS Health, DR Vitamin Solutions, Natural Ophthalmics, OcluMed, Similasan, TRP Company and Walgreens Boots Alliance.

After initial stumbles, Moderna finally gains clean phase 3 win for mRNA flu shot

After tweaking the formula behind an mRNA flu vaccine, Moderna has finally met all the goals needed for a successful shot in a phase 3 trial. Now, CEO Stéphane Bancel is eyeing a launch as early as 2024. 

Moderna follows AstraZeneca's lead, dumping 2 previously shared programs—plus 2 more

Right after making headlines for a phase 3 mRNA flu shot win, Moderna shared that it’s axing four clinical assets from its pipeline—including two AstraZeneca dumped last year.

AbbVie's Skyrizi deals heavy blow to J&J's Stelara in head-to-head Crohn's disease study

AbbVie’s next-generation anti-inflammation drug Skyrizi has been acing clinical trials left and right. The latest? The antibody drug is applying pressure on Johnson & Johnson’s Stelara with a successful head-to-head study in Crohn’s disease.

Orthofix board gives CEO, other C-suite members the boot for 'offensive conduct'

The spine and orthopedics company said that President and CEO Keith Valentine, Chief Financial Officer John Bostjancic and Chief Legal Officer Patrick Keran will be replaced, effective immediately.

Pfizer CEO throws weight behind migraine awareness campaign, pushing supportive employer message

Pfizer CEO Albert Bourla has thrown his weight behind a disease awareness campaign, using his handles on social media platforms to amplify messaging about the importance of migraine-friendly work policies.

Part-human, part-pig kidneys grown in pig embryos for the first time

While science is still a long way off from using animals as incubators for human organs—a prospect that's rife with ethical dilemmas—the development marks a milestone for transplant medicine.

Novartis pulls Sandimmune batch after crystals formed in bottles, posing safety risks

A potentially dangerous crystal formation was found in a bottle of the drug, which is used to prevent organ rejections in transplant patients.
 
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'The Top Line': Trends at Cannes Lions, the top compensated CEOs in the industry, and the cancer drug shortage

This week on "The Top Line," we discuss the trends seen at Cannes Lions, the top compensated CEOs in the industry, and the cancer drug shortage
 

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Plan for success with your process liquid and buffer preparation

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