Lab demand shrinks with biotech reset

Today’s Big News

Sep 20, 2023

Merck KGaA doubles up on AI partners, tapping BenevolentAI and Exscientia for drug discovery push


Fresh Tracks to dissolve after hunt for buyer comes up empty


Genentech sees more potential in peptides, signs $1B biobucks deal with PeptiDream


Lab demand shrinks in life sciences real estate market, putting keys in hands of smaller biotechs


'All the Christmases rolled into one': Bone loss prevented in mice while in microgravity


Genentech sticks molecular deal with Belgian biotech for $47M upfront


Ex-Nkarta exec Nadir Mahmood rises to first CEO role at UCSF spinout Rezo


NightHawk dives into CDMO business, leaving R&D staffers in the lurch


Taysha ends work on gene therapy after Astellas walks away, FDA requests randomized trial


After phase 3 failures, Relmada hopes open-label look at depression drug assuages investors

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Featured

Merck KGaA doubles up on AI partners, tapping BenevolentAI and Exscientia for drug discovery push

Merck KGaA is spreading its bets on an artificial-intelligence-enabled future for drug discovery, inking similar three-target deals with BenevolentAI and Exscientia. The deals are collectively worth more than $30 million upfront and $1 billion in potential milestones.
 

Top Stories

Fresh Tracks to dissolve after hunt for buyer comes up empty

Fresh Tracks Therapeutics is dissolving after spending months searching for alternatives, with the company’s board unanimously approving a liquidation plan.

Genentech sees more potential in peptides, signs $1B biobucks deal with PeptiDream

PeptiDream is clearly doing something right. Big Pharmas have been queueing round the block to collaborate on the Japanese biotech’s peptide discovery platform, and, now, long-term partner Genentech is back with $40 million in upfront cash for a fresh licensing agreement.

Health Equity: IHI and Genentech on the Need for an Industry-Wide Approach

Two leaders supporting the Rise to Health Coalition discuss the need for coordinated and collective action across sectors to advance health equity

Lab demand shrinks in life sciences real estate market, putting keys in hands of smaller biotechs

Boston, the San Francisco Bay Area and San Diego are once again the top markets for life sciences commercial real estate in the U.S., with plenty of opportunities for growth as biotech readies for a comeback, according to a new report.

'All the Christmases rolled into one': Bone loss prevented in mice while in microgravity

Astronauts in space lose bone at a rate of about 1% per month on average—twelve times the rate of people on Earth. Researchers sent mice into microgravity to test a new drug.

Genentech sticks molecular deal with Belgian biotech for $47M upfront

Only hours after the Roche unit signed a radiopharmaceutical-focused pact with longtime collaborator PeptiDream, it’s now handed over $47 million to enter the molecular glue space.

Ex-Nkarta exec Nadir Mahmood rises to first CEO role at UCSF spinout Rezo

Nadir Mahmood is taking his first CEO gig leading Rezo Therapeutics, which spun out of UCSF and is chaired by longtime biotech exec George Scangos.

NightHawk dives into CDMO business, leaving R&D staffers in the lurch

NightHawk Biosciences, a biotech that was developing medical countermeasures to defend against emerging biothreats, is officially dropping R&D and sending associated staff out the door to fully focus on its CDMO wing.

Taysha ends work on gene therapy after Astellas walks away, FDA requests randomized trial

Astellas has turned down the chance to option an asset from Taysha Gene Therapies. And with Taysha identifying study design feasibility challenges after talking with the FDA, the biotech has stopped internal development of the candidate and added it to a large pile of dropped and deprioritized programs.

After phase 3 failures, Relmada hopes open-label look at depression drug assuages investors

After flunking two phase 3 trials, Relmada has turned over the open-label card for its depression med providing the first bit of optimism in months, if not years, for the central-nervous-system-focused biotech. 

In new lawsuits, Lilly accuses 8 companies of making and selling compounded versions of Mounjaro

Early this summer, Novo Nordisk filed multiple lawsuits accusing companies of producing and selling compounded versions of Ozempic and Wegovy. Now, Eli Lilly has done the same, filing eight separate complaints in five states.
 
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This week on "The Top Line," we discuss the trends seen at Cannes Lions, the top compensated CEOs in the industry, and the cancer drug shortage
 

Resources

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An Introduction to Organ-on-a-Chip Technology

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Unlock potential in buffer preparation

Learn how outsourcing the buffer preparation can reallocate resources to support core activities of your bioprocess production.
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What Are the Benefits of Generative AI for Pharma?

From trial site feasibility and patient populations to data analysis, generative AI has the potential to revolutionize drug discovery and clinical trial recruitment at both the therapeutic area and indication level.
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Discovering High-Affinity, Functional Anti-GLP-1R Antibodies

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Transitioning from using RUO to cGMP chemicals for clinical trials

By 2030, the global demand for biologics is projected to grow at a CAGR of 8.7% and the challenges, risks, and costs of bringing large molecule products to market are growing exponentially.

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Biotech in the UK: Mapping the Runway to Success

15 biotech executives from the Cambridge area discuss the current biotech landscape, as well as challenges, opportunities, and best practices for emerging biotech companies seeking success in the UK and beyond.
 

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