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October 05, 2016

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Today's Rundown

  1. Novartis to move R&D tropical disease base out of Singapore, cut Zurich, Shanghai jobs

  2. Genzyme vet joins CRISPR player Editas as CMO

  3. Insmed licenses AstraZeneca’s early-stage lung med in $150M-plus deal

  4. U.K. cancer charity, investment firm launch neoantigen biotech

  5. Lexicon to settle down with Symphony as it aims for early 2017 FDA approval

  6. Bone Therapeutics posts interim PhIIa data, building case for bone-forming cell therapy

  7. From FierceMedicalDevices: Trinity Biotech yanks FDA submission for point-of-care heart failure test

  8. From FierceBiotechResearch: CAR-T cells can be effective protein delivery vehicles to treat lymphoma

Featured Story

Novartis to move R&D tropical disease base out of Singapore, cut Zurich, Shanghai jobs

Novartis will move its Singapore research base for dengue fever and malaria over to California, and is set to reduce headcount at its Zurich facility and its China biologics group.


Top Stories

Genzyme vet joins CRISPR player Editas as CMO

Tuesday, October 4, 2016

Editas Medicine has nabbed former VP of rare disease clinical development Dr. Gerald Cox from Sanofi’s Genzyme to become its CMO.

Insmed licenses AstraZeneca’s early-stage lung med in $150M-plus deal

Wednesday, October 5, 2016

After handing over development of its experimental GI treatment MEDI2070 to Allergan this week, AstraZeneca has struck another licensing deal, this time with biotech Insmed and its respiratory candidate AZD7986.

U.K. cancer charity, investment firm launch neoantigen biotech

Wednesday, October 5, 2016

Cancer Research UK and London investment firm Syncona have joined forces to fund and launch a new neoantigen-focused lung cancer biotech.

Lexicon to settle down with Symphony as it aims for early 2017 FDA approval

Wednesday, October 5, 2016

The Texas-based company has now made arrangements to pay its final obligations to Symphony Icon upon an FDA approval of telotristat ethyl to treat carcinoid syndrome.

Bone Therapeutics posts interim PhIIa data, building case for bone-forming cell therapy

Wednesday, October 5, 2016

Bone Therapeutics has posted an interim look at data from a small Phase IIa trial of its allogeneic cell therapy in lumbar spinal fusion. The vertebral bodies fused in all 8 of the subjects to complete one year of follow up, putting Bone Therapeutics on a path it hopes will lead to a series of positive data readouts in 2017.

Trinity Biotech yanks FDA submission for point-of-care heart failure test

Wednesday, October 5, 2016

Trinity Biotech has traveled a rough road with its point-of-care test for heart failure, and now, it’s reached the bitter end. The company is pulling back its FDA submission for the device after regulators voiced some concerns about the diagnostic.

CAR-T cells can be effective protein delivery vehicles to treat lymphoma

Wednesday, October 5, 2016

Researchers at Memorial Sloan Kettering have discovered something new about CAR-T immunotherapy: The cells can act as delivery vehicles for proteins that have the potential to treat lymphoma.

News of Note

Codexis has finished off the handover of its CodeEvolver protein engineering platform tech to Merck, gaining an $8 million payment from the U.S. Big Pharma. Release

Catabasis Pharmaceuticals has made a brace of promotions as Andrew Nichols becomes its new CSO while Angelika Fretzen steps up to be the SVP of product development. Statement

California biotech Regulus Therapeutics has also made a new appointment, that of Timothy Wright, who becomes its new chief R&D officer. Release

NJ-based Immunomedics has priced an underwritten offering of 10 million shares of common stock and warrants as it looks to make $30 million. Statement

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[Webinar] The Basics of Biotech 101, 201 & 301 - Price: $299

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[Whitepaper] Complimentary IDMP Report from Gartner

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Gartner research on short- and long-term strategies for IDMP compliance.

Events

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