ICYMI: Lilly shakes up leadership

Today’s Big News

Oct 6, 2023

Flush with Wegovy cash, Novo Nordisk's owner widens investment strategy beyond biotech


Eye disease biotech Atsena downsizes to save money for retinal program testing new capsid


Chutes & Ladders—Lilly's US leader takes charge of key diabetes and obesity unit


'The Top Line': Opportunities, challenges and uncharted territory in pharma marketing


BMS taps Arch-backed startup to change cancer trial Paradigm, accelerate enrollment

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

Flush with Wegovy cash, Novo Nordisk's owner widens investment strategy beyond biotech

Outside of a global pandemic, it’s rare for a medicine to truly become a household name. But Novo Nordisk’s Wegovy is rapidly reaching that status, with the obesity drug accruing more front pages and celebrity endorsers every day.
 

Top Stories

Eye disease biotech Atsena downsizes to save money for retinal program testing new capsid

Atsena Therapeutics has cut staff to funnel more money toward an inherited retinal disease program that just began dosing for a phase 1/2 trial in August.

Chutes & Ladders—Lilly's US leader takes charge of key diabetes and obesity unit

With Eli Lilly on the precipice of one of its most consequential FDA approvals ever, the company is making major executive moves. 

'The Top Line': Opportunities, challenges and uncharted territory in pharma marketing

In this episode of "The Top Line," we delve into the uncharted territory that pharma marketers face, from harnessing AI's potential to navigating the Inflation Reduction Act.

BMS taps Arch-backed startup to change cancer trial Paradigm, accelerate enrollment

Bristol Myers Squibb is putting Paradigm’s plans to rebuild the clinical trial system to the test, teaming up with the startup to design studies that can activate community health provider organizations as sites.

After short FTC fight, Amgen wraps up $27.8B Horizon buyout

Amgen has completed its $27.8 billion acquisition of Horizon Therapeutics after fending off a legal challenge by the U.S. antitrust watchdog.

Amgen's Lumakras flunks FDA expert meeting, but market withdrawal looks unlikely for now

Judgment Day has come for Amgen’s first-in-class KRAS inhibitor Lumakras as the FDA’s Oncologic Drugs Advisory Committee gathered Thursday to weigh the merits of the cancer med’s phase 3 clinical trial CodeBreak 200.

So why is the medical device lobby suing the Library of Congress?

The Library of Congress has recently become a battleground over the right to repair, including for high-tech imaging machines and surgical robots.

Fierce Pharma Asia—Takeda's cancer drug withdrawal; Kyowa Kirin's gene therapy buy; Biogen's biosim nod

Takeda will withdraw lung cancer drug Exkivity after a confirmatory trial failure. Kyowa Kirin is buying gene therapy biotech Orchard Therapeutics. Biogen's biosimilar version of Roche's Actemra, bought from Bio-Thera Solutions, won an FDA nod. And more.
 
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'The Top Line': Opportunities, challenges and uncharted territory in pharma marketing

In this episode of "The Top Line," we delve into the uncharted territory that pharma marketers face, from harnessing AI's potential to navigating the Inflation Reduction Act.
 

Resources

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From Lead Optimization to Drug Candidate Triage: A Data-Driven Approach to Drug Discovery

Embark on an in-depth journey through the pivotal Make-Test-Decide Workflow, where collaboration and data-driven decisions play a paramount role in the intricate landscape of drug discovery. Watch now to learn how cloud implementation fosters accessibility and collaboration, revolutionizing research across locations and companies.
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Improving yield and reproducibility with advanced sample prep

Learn how to get better results from suboptimal biospecimens for NGS and protein analysis.
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Ensuring a Reliable Biopharmaceutical Supply in the EU

Economic and regulatory factors are making biopharma supply chains more complex in the EU. This paper explores strategies that biopharma companies can use to better manage complexity, cost, and risk.
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Biology Informatics Solutions Brochure

From Assay Development Through Large Molecule Development. Streamline your R&D workflows and gain valuable insights with our Biology Solutions Brochure. Download now to discover how to control your laboratory workflows across various assay techniques, modalities, and data types.
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An Introduction to Organ-on-a-Chip Technology

Emulate in vivo biology with next-generation in vitro technology.
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Five ways to get the most from your lab and manufacturing facilities

Learn more about how you can improve the productivity of your research and manufacturing operations and accelerate the journey from laboratory to saving lives.

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Unlock potential in buffer preparation

Learn how outsourcing the buffer preparation can reallocate resources to support core activities of your bioprocess production.
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What Are the Benefits of Generative AI for Pharma?

From trial site feasibility and patient populations to data analysis, generative AI has the potential to revolutionize drug discovery and clinical trial recruitment at both the therapeutic area and indication level.
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Discovering High-Affinity, Functional Anti-GLP-1R Antibodies

Learn how a GPCR-focused library with a cell-based biopanning strategy led to the discovery of 13 high-affinity and selective anti-GLP-1R antibodies with highly developable therapeutic properties.

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Transitioning from using RUO to cGMP chemicals for clinical trials

By 2030, the global demand for biologics is projected to grow at a CAGR of 8.7% and the challenges, risks, and costs of bringing large molecule products to market are growing exponentially.

 

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