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October 07, 2016

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Today's Rundown

  1. Clovis reveals ovarian cancer data underlying upcoming FDA review

  2. German Merck inks Vaccinex PD-L1-anti-semaphorin 4D IgG4 combo trial deal

  3. MIT spinout bumps up Series A to $12M+ for novel I/O discovery

  4. Newron raises CHF26M to wrap up PhII schizophrenia trial, late-phase CNS study

  5. Brexit hits European life science M&A in Q3, as smaller deals set to become the norm

  6. From FierceMedicalDevices: Obalon Therapeutics launches $75M IPO for ingestible weight loss balloon

  7. EuroBiotech Report: Amgen-Nuevolution, $95M Series A, Medicxi, Boehringer and PhII data

  8. Chutes and Ladders: Editas nabs Genzyme’s former rare diseases VP Gerald Cox as CMO

Featured Story

Clovis reveals ovarian cancer data underlying upcoming FDA review

Clovis Oncology is set for an FDA review date of February 23 for lead candidate rucaparib. It’s under priority review as a monotherapy in a tough-to-treat group: ovarian cancer patients with BRCA-mutated tumors inclusive of both germline and somatic BRCA mutations who have been treated with two or more chemotherapies.


Top Stories

German Merck inks Vaccinex PD-L1-anti-semaphorin 4D IgG4 combo trial deal

Friday, October 7, 2016

The word in cancer right now is combination, and Merck KGaA, coming in the same week it opened a new life science R&D collab center in Korea, is joining forces in the lab with Vaccinex to see if together their investigational meds can help patients with lung cancer live longer.

MIT spinout bumps up Series A to $12M+ for novel I/O discovery

Thursday, October 6, 2016

Philadelphia, PA-based Immunome has raised $5 million of a Series A round in April that it now said will hit $12.2 million.

Newron raises CHF26M to wrap up PhII schizophrenia trial, late-phase CNS study

Friday, October 7, 2016

Newron Pharmaceuticals has tapped investors for CHF 26.1 million to see it through to data readouts on a couple of key pipeline programs. The funding extends Newron’s financial runway out beyond the completion of a Phase IIa schizophrenia trial and Phase II/III orphan CNS disease study.

Brexit hits European life science M&A in Q3, as smaller deals set to become the norm

Friday, October 7, 2016

In the first quarter after Britain voted to leave the European Union, life sciences deals took a nosedive--and while Asia booked impressive surges in M&A activity, the U.S. also saw a drop in deals as tax inversion rules and pricing pressures kick in.

Obalon Therapeutics launches $75M IPO for ingestible weight loss balloon

Thursday, October 6, 2016

Obalon Therapeutics is making its market debut, launching an IPO of $75 million to fuel U.S. commercialization of its weight loss balloon device.

EuroBiotech Report: Amgen-Nuevolution, $95M Series A, Medicxi, Boehringer and PhII data

Thursday, October 6, 2016

Amgen and Nuevolution pen an R&D pact, ambitious Carrick raises $95 million, Medicxi founds Kymo, and more.

Chutes and Ladders: Editas nabs Genzyme’s former rare diseases VP Gerald Cox as CMO

Thursday, October 6, 2016

Genzyme's former VP becomes Editas' CMO, SynteractHCR makes three high-profile appointments, Michael Rogers steps down as Acorda’s CFO. Plus more hirings, firings and retirings throughout the industry.

News of Note

Israel's Alcobra has received a formal FDA clinical hold letter for its Phase III test of MDX in ADHD patients after “electrophysiological neurologic findings” were found in some animal studies. Release

Obesity biotech Nexus BioPharma has signed a deal with TransChem for its transition state chemistry tech for kinase inhibition. Statement

Cancer and rare disease firm Idera Pharmaceuticals has priced an underwritten public offering of 25 million shares of common stock at a price of $2 apiece. Release

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[Research] Bioprocessing Market Trends and Outsourcing Dynamics: 2016-2021

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ISR’s CRO Quality Benchmarking – Phase II/III Service Providers (8th Edition) report provides a Consumer Reports-style analysis of Phase II/III CRO service quality from hundreds of users who rated 44 Phase II/III CROs across 26 critical dimensions of quality.

[Whitepaper] Ensuring the Greatest Return From Your Poorly Soluble Molecule

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[Webinar] The Basics of Biotech 101, 201 & 301 - Price: $299

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This 3-part webinar series is specifically geared toward the non-science professional who needs to better understand industry terminology, science, techniques and issues.

[Whitepaper] Complimentary IDMP Report from Gartner

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Gartner research on short- and long-term strategies for IDMP compliance.

Events

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