Vicious Cycle: Vanda denies buyout bid again

Today’s Big News

Oct 14, 2024

Leqembi's vial design could result in hundreds of millions in annual Medicare waste: study


Lundbeck signs $2.5B check for Longboard, seeing blockbuster potential in epilepsy med


Vanda, despite FDA rejection, swats down another buyout bid from Cycle


Novartis channels Gargamel, terminating midphase SMURF1 trial


BMS, Pfizer, Regeneron, Cardinal Health and more back ‘enhanced’ thrombosis awareness campaign


CMR Surgical lands FDA clearance for Versius robot amid CEO swap

 

Featured

Leqembi's vial design could result in hundreds of millions in annual Medicare waste: study

As payers tally up the potential costs of anti-amyloid antibodies for Alzheimer’s disease, a new study suggests that the vial design for Eisai and Biogen’s Leqembi could result in hundreds of millions of dollars in wasted spending each year for Medicare.
 

Top Stories

Lundbeck signs $2.5B check for Longboard, seeing blockbuster potential in epilepsy med

After spying blockbuster potential in Longboard Pharmaceuticals’ epilepsy med, brain disease-focused pharma Lundbeck is scooping up the biotech for $2.5 billion.

Vanda, despite FDA rejection, swats down another buyout bid from Cycle

The FDA’s rejection of Vanda Pharmaceuticals’ stomach disease candidate has done little to dampen the enthusiasm of England’s Cycle Pharmaceuticals to acquire the Washington D.C.-based company. On Monday, Vanda revealed that it has turned down a second $8-per-share takeover offer from Cycle, which works out to a $488-million deal to buy out the 18-year-old pharma.

Novartis channels Gargamel, terminating midphase SMURF1 trial

Novartis has terminated a phase 2 trial of its SMURF1 inhibitor LTP001 in idiopathic pulmonary fibrosis but will continue to advance the candidate in another indication.

BMS, Pfizer, Regeneron, Cardinal Health and more back ‘enhanced’ thrombosis awareness campaign

Big Pharmas, medical device companies and healthcare groups have teamed up with the International Society on Thrombosis and Haemostasis (ISTH) for a new campaign aimed at boosting awareness about how to spot and treat blood clots.

CMR Surgical lands FDA clearance for Versius robot amid CEO swap

CMR Surgical obtained a de novo clearance from the FDA for its Versius surgical system, allowing its modular laparoscopic robot to enter U.S. shores.

On road to crowded Crohn's disease market, Lilly's Omvoh bests J&J's Stelara in head-to-head study

Eli Lilly's drug outperformed Johnson & Johnson's established Stelara in a phase 3 study that looked at histologic disease responses over 52 weeks.

GSK's depemokimab reduces polyps in phase 3 trials, adding weight to upcoming filing

GSK’s blockbuster hopes for depemokimab remain on track after the investigational long-acting asthma treatment has also been shown to reduce nasal polyps in a pair of phase 3 trials.

Incyte picks Dr. Pimple Popper to expand Opzelura atopic dermatitis campaign

A year after kicking off a star-studded campaign to highlight the stories of real patients with atopic dermatitis, Incyte has expanded it to represent even more patients—including a very recognizable face in the world of skin health.

With election nearing, BMO analysts don't expect major pharma shake-ups from either candidate

While a Trump win could be slightly more positive for the industry, neither candidate is expected to make significant waves in the sector due to a divided congress and the already-passed Inflation Reduction Act.

Transgene's viral cancer vaccine flunks midphase test—but subgroup signal spurs ongoing analysis

Transgene’s therapeutic vaccine candidate TG4001 has flunked a phase 2 solid tumor trial. But, while the prospect failed to improve progression-free survival, the biotech is continuing to analyze aspects of the data including a “positive efficacy trend” in a prespecified subgroup before deciding on its next steps.
 
Fierce podcasts

Don’t miss an episode

A revival in neuro therapeutics

This week on "The Top Line," Fierce Pharma's Fraiser Kansteiner chats with industry leaders about the surge in neuroscience investment, breakthroughs and future targets in neuropharmaceuticals.
 

Resources

eBook

Decoding the data

Need the superpowers to select the right lab equipment?
Whitepaper

Strategies to Optimize Expression Challenges of Multi-chain and Bispecific Antibodies

Take a brief journey through some of the efforts that Lonza has made to optimize the manufacturability of bsAbs and other formats, and take a glance towards future directions with an emphasis on the upstream aspects.
Whitepaper

Communicating the Value of Biopharma Assets to Potential Investors

How can an emerging company attract the right partner for a therapeutic asset (& optimize its value in a transaction)? This paper offers some insights.
Whitepaper

Accelerating Timelines to Clinic with GPEx® Lightning

Unlock the Future of Biotherapeutics with Catalent Biologics!
Whitepaper

Epilepsy Clinical Trials

Finding an effective epilepsy treatment can be arduous. Download this brochure to delve into how IQVIA's expertise and innovative strategic approach can streamline the clinical trial process, helping to get new therapies to patients who need them sooner.
 

Industry Events

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

Upcoming Fierce Events

18-19
Nov
Free Virtual Event
20
Nov
Free Virtual Event
4
Dec
Free Virtual Event
5
Dec
The Lighthouse at Pier 61 in New York City
14-15
Jan
San Francisco, CA

View all events