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October 18, 2019___

Today's Rundown

Featured Story

Mirati sets date for closely watched clinical KRAS readout

Mirati Therapeutics is set to reveal the first clinical data on its closely watched KRAS G12C inhibitor MRTX849 Oct. 28. The readout is a key moment in the fairly short history of the drug and Mirati, shares in which have soared in the updraft created by data on Amgen’s rival asset. 

Top Stories

UCB's bispecific beats J&J's Stelara in psoriasis phase 3 

UCB’s bimekizumab has beaten Johnson & Johnson’s Stelara in a phase 3 psoriasis trial. The bispecific inhibitor of IL-17A and IL-17F outperformed J&J’s blockbuster incumbent against an endpoint that tracked the proportion of patients achieving a 90% reduction in psoriasis symptoms.

Gilead, Spring Bank’s Hep B combo shows ‘incremental benefit,’ but all eyes on higher doses: analysts

Spring Bank Pharmaceuticals’ hepatitis B drug, given in tandem with Gilead’s Vemlidy, tamped down on chronic disease in more than one-fifth of patients in a phase 2 study—a result that Jefferies analysts called an “incremental positive benefit” over either drug alone. The data set the stage for potentially better performances from higher doses.

[Sponsored] A New Starting Point for Patient Support: Technology-Driven Hub Services

Flipping the script for specialty medications – improved patient access and time-to-therapy with a new tech-enabled platform from CoverMyMeds and RxCrossroads by McKesson.

Blocking tumor evolution to halt cancer drug resistance

Researchers are developing a new class of drug to block the tumor DNA mutations that allow certain cancer cells to avoid the body’s immune responses and treatments, which can lead to the proliferation of hard-to-kill, drug-resistant strains.

EuroBiotech Report—Healx and Abalos raise cash, Ipsen bags Blueprint drug, Gilead and ReNeuron

In this week's EuroBiotech Report, Healx raises $56 million, Boehringer's VC wing backs anti-cancer virus startup and Ipsen bags Blueprint drug.

FiercePharmaAsia—Daiichi, AZ's FDA priority review; Torrent's 'sartan' mess; Takeda-Acino deal

AstraZeneca and Daiichi Sankyo's breast cancer antibody-drug conjugate gets an FDA priority review. FDA publicly slams Torrent Pharma as a main culprit in the global recall of tainted "sartan" drugs. Takeda sells some 30 emerging markets drugs to Swiss firm Acino International. And more.

Chutes & Ladders—Gilead Sciences names Dickinson to CFO role

Gilead names Dickinson to CFO role; MedImmune CSO Herbst nabs CSO job at Pyxis; Checkmate picks up Wooldridge for CMO.

Resources

[Article] 8 Compelling Reasons Why Businesses Need To Be In The Cloud Now!

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Download this report for full details of Life sciences M&As in the second quarter of 2019 with notes and trends.

[Whitepaper] SOAR™ Model Manages Data From Source to Submission

Find out how it leverages real-world data and novel IntElligo Research Stack™ technology to help researchers battle rising costs, cumbersome processes, and stagnant participation — bridging the gap between research and care.

[Whitepaper] Successful Clinical Trials in the Era of Genetics-based Medicine

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[Whitepaper] Synthesizing Success: Six Principles for Getting Pharmaceutical Development Right from the Start

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[Whitepaper] Advanced Analytical Approaches for Accelerated Development of Gene Therapy Products

Download the White Paper and learn how detailed characterization can guide successful development of gene therapy products.

[Whitepaper] Webinar Benchmarks Report for Life Sciences 2019

Compare digital program performance and audience engagement among your life sciences peers.

[Webinar] Clinically Integrated Networks: A Growing Disruptor in American Healthcare

Clinically Integrated Networks are vehicles for powerful IDNs to extend their influence into the physician sector and play a key role for IDNs trying to pave a path to becoming a self-contained healthcare ecosystem.

[Whitepaper] Fail Fast. Succeed Faster.

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[Whitepaper] Innovative Funding Models for Treatment of Cancer and Other High-Cost Chronic Noncommunicable Diseases

A global landscape study of funding trends and innovations.

[Whitepaper] Understanding Precision Medicine in Oncology

White paper providing an overview of precision medicine in oncology, as well as a look ahead at future developments and keys to success for pharmaceutical and diagnostics companies.

[Case Study] Clinical Supply Management

Download the case study to learn about the clinical supply management tools that helped a small sized pharma company during phase III of a multi-arm oncology study.

[Video] Demand Led Services and Clinical Supply Efficiency

Watch a short video on demand led supply model. It is designed to meet the needs of patients, clinical sites, clinical team and sponsors and results in shorter lead time, less waste, less stock out risk and no booklet labels.

[eBook] Strategies for Efficient Clinical Supply Management and Forecasting

Download the eBook to explore a proactive approach for clinical supply management.

Events