AM-Pharma flunks phase 3 kidney injury test

Today's Big News

Oct 20, 2022

CDC advisory panel recommends adding COVID vaccine to kids’ routine immunization schedule 

J&J, Legend's Carvykti delivers encouraging early growth ahead of key myeloma readout 

AM-Pharma, once a Pfizer takeover target, flunks phase 3 kidney injury trial 

NIH study finds Black patients receive end-stage heart failure treatments at half the rate of white patients 

CDC and Fox News pundit Carlson spar in Twitter tangle over COVID vaccine recommendation for kids 

Plan sponsors' satisfaction with PBMs is declining, a new survey shows. Here's why 

Prime time for IPO as gene editing biotech goes public with $175M 

Windows, layout and other hospital room features play a role in surgical patients' clinical outcomes, study finds 

Pfizer CEO Bourla says company ready to execute in a 'pivotal' 2023: report 

With $255M antibody biotech buy, AbbVie spies opportunity to take on tricky GPCRs 

Cordis to absorb drug-eluting balloon maker MedAlliance for $235M upfront 

FDA clears Intelligent Ultrasound’s AI for real-time guidance in nerve block injections 

Gilead’s Kite ties itself to Refuge’s gene expression platform in blood cancer CAR-T deal

 

Featured

CDC advisory panel recommends adding COVID vaccine to kids' routine immunization schedule

The Advisory Committee on Immunization Practices, a CDC advisory panel made up of medical and scientific experts, yesterday recommended that the COVID-19 vaccine become part of a child’s vaccination schedule.
 

Top Stories

J&J, Legend's Carvykti delivers encouraging early growth ahead of key myeloma readout

In hot pursuit of Bristol Myers Squibb and 2seventy bio’s first-to-market Abecma, Johnson & Johnson and Legend Biotech’s CAR-T therapy Caryvkti has shown an encouraging sign of growth.

AM-Pharma, once a Pfizer takeover target, flunks phase 3 kidney injury trial

Pfizer may have dodged a bullet by walking away from AM-Pharma. The biotech, a onetime takeover target for the Big Pharma, has stopped a phase 3 clinical trial of its kidney injury candidate early after it failed an interim futility analysis.

NIH study finds Black patients receive end-stage heart failure treatments at half the rate of white patients

A study published this week highlights yet another area of potential racial bias in healthcare: end-stage heart failure therapies, where white patients were found to receive life-extending treatments at distinctly higher rates compared to Black patients.

CDC and Fox News pundit Carlson spar in Twitter tangle over COVID vaccine recommendation for kids

The CDC took the unusual step of going to Twitter on Wednesday to correct a Fox News report that claimed the agency was set to require schoolchildren to receive COVID-19 vaccines. Additionally, a CDC advisory committee voted unanimously to provide COVID shots for free to children under the age of 19 who can’t afford them.

Plan sponsors' satisfaction with PBMs is declining, a new survey shows. Here's why

Satisfaction with pharmacy benefit managers is on the decline, particularly among health plans, a new survey shows.

Prime time for IPO as gene editing biotech goes public with $175M

Gene editing biotech Prime Medicine is turning up the heat, melting some of the frosty market waters with a $175 million IPO, one of the sector’s largest debuts this year, especially for a preclinical company with no human data to fuel fundraises.  

Windows, layout and other hospital room features play a role in surgical patients' clinical outcomes, study finds

Occupancy, distance to a nursing station and easy line of sight into a hospital room may all be worth considering when assigning surgical patients a hospital room, according to a single-center study of nearly 4,000 surgical patients presented this week.

Pfizer CEO Bourla says company ready to execute in a 'pivotal' 2023: report

After Pfizer launched to pandemic superstar status with its BioNTech-partnered COVID-19 vaccine, Comirnaty, the company has something to prove with its next few launches. And next year is setting up to be a pivotal year for the drugmaker, one that could feature up to 10 new launches, its CEO said.

With $255M antibody biotech buy, AbbVie spies opportunity to take on tricky GPCRs

AbbVie is paying $255 million cash to acquire DJS Antibodies and the British biotech's platform for targeting transmembrane proteins.

Cordis to absorb drug-eluting balloon maker MedAlliance for $235M upfront

The transaction for the Swiss manufacturer MedAlliance could total as much as $1.1 billion over the next seven years.

FDA clears Intelligent Ultrasound’s AI for real-time guidance in nerve block injections

The FDA doled out a de novo clearance to the ScanNav Anatomy PNB device to help guide the precise delivery of peripheral nerve block injections.

Gilead's Kite ties itself to Refuge's gene expression platform in blood cancer CAR-T deal

Gilead’s Kite Pharma has tied down a licensing deal for Refuge Biotechnologies’ gene expression platform in hopes of developing new blood cancer treatments, potentially setting flight to a new generation of CAR-Ts.
 
Fierce podcasts

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'The Top Line': The most productive pharmas, Biogen's leadership

This week on "The Top Line," we talk about our latest analysis on the world’s most productive biopharmas. We also discuss Biogen's tumultuous year and who it is considering for a new CEO.

 

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