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October 23, 2019___

Today's Rundown

Featured Story

‘Trick or Treat?’ Analysts react to Biogen’s aducanumab surprise

Biogen stunned investors and analysts alike on Tuesday when it said it would file its Alzheimer's medaducanumab for approval, despite canning two phase 3 studies for the drug after a futility analysis. Now that the dust has settled, what are analysts saying?

Top Stories

Rapt Therapeutics revives IPO, files to raise $75M

Second time might be the charm for Rapt Therapeutics, which filed to raise up to $75 million in its IPO after postponing an earlier attempt in August. This move comes after the company renamed itself and filed its initial S-1 form with plans to reap up to $86 million in its Nasdaq debut.

Novartis bets $80M on Pliant's preclinical NASH prospect

Novartis has put up $80 million to land the global license to Pliant Therapeutics’ preclinical nonalcoholic steatohepatitis (NASH) asset and three additional candidates. The NASH drug, PLN-1474, is a small molecule inhibitor of integrin αVβ1 Pliant thinks can reduce the growth of fibrotic tissue in the liver.

[Sponsored] Advancing Site-Sponsor Relationships

Clinical trials involve massive complexity and, often, systems that lack consistency and discipline. With a new perspective to an old problem, WCG coordinates the execution of six proven strategies to dramatically and consistently bring clinical studies to launch faster and at a lower cost.

Evotec brings early stage accelerator model to Israel

Evotec has expanded its model for accelerating early-stage academic research to Israel. The creation of the latest outpost of the BRIDGE model sees Evotec team up with Integra Holdings and Yissum to help researchers at the Hebrew University of Jerusalem translate their work.

After phase 3 bust, Lilly cans pancreatic cancer program for Armo buyout drug

Eli Lilly is canning the lead program for the crown jewel of its $1.6 billion Armo Biosciences buyout after the drug put up a poor showing in pancreatic cancer. The Big Pharma said it was ending the phase 3 study of pegilodecakin in its third-quarter earnings presentation.

Amgen CFO David Meline, overseer of major restructuring, to retire

In the second half of 2014, Amgen initiated a major overhaul aimed at cutting costs and boosting R&D activities. Now, the chief financial officer tapped on the eve of the revamp is set to bid adieu after successfully turning around the big biotech's financial numbers.

Resources

[Article] 8 Compelling Reasons Why Businesses Need To Be In The Cloud Now!

Companies that don’t have a cloud strategy are at a competitive disadvantage. Why? The cloud has a measurable impact on business.

[Whitepaper] The Next Generation of Trial Master File Systems

Simplified filing, improved oversight, audit readiness: is your eTMF system delivering best-in-class benefits?

[Whitepaper] Implementing On-Dose Authentication Technologies for Solid Dose Drug Products

Learn about how you better manage product authentication and battle drug counterfeiting with innovative solutions.

[Whitepaper] Cortellis Q2 2019 M&A report

Download this report for full details of Life sciences M&As in the second quarter of 2019 with notes and trends.

[Whitepaper] SOAR™ Model Manages Data From Source to Submission

Find out how it leverages real-world data and novel IntElligo Research Stack™ technology to help researchers battle rising costs, cumbersome processes, and stagnant participation — bridging the gap between research and care.

[Whitepaper] Successful Clinical Trials in the Era of Genetics-based Medicine

Download this complimentary guide paper that explores key strategies for a successful genetics-informed clinical trial.

[Whitepaper] Best Practices for Incorporating Real World Imaging Data into RWE Programs

The time has finally come when medical imaging can be effectively utilized into the RWE process. Read the whitepaper on the best practices for incorporating Real World Imaging.™

[Whitepaper] Synthesizing Success: Six Principles for Getting Pharmaceutical Development Right from the Start

Is your API development on track?

[Whitepaper] Webinar Benchmarks Report for Life Sciences 2019

Compare digital program performance and audience engagement among your life sciences peers.

[Webinar] Clinically Integrated Networks: A Growing Disruptor in American Healthcare

Clinically Integrated Networks are vehicles for powerful IDNs to extend their influence into the physician sector and play a key role for IDNs trying to pave a path to becoming a self-contained healthcare ecosystem.

[Whitepaper] Innovative Funding Models for Treatment of Cancer and Other High-Cost Chronic Noncommunicable Diseases

A global landscape study of funding trends and innovations.

[Case Study] Clinical Supply Management

Download the case study to learn about the clinical supply management tools that helped a small sized pharma company during phase III of a multi-arm oncology study.

[Video] Demand Led Services and Clinical Supply Efficiency

Watch a short video on demand led supply model. It is designed to meet the needs of patients, clinical sites, clinical team and sponsors and results in shorter lead time, less waste, less stock out risk and no booklet labels.

[eBook] Strategies for Efficient Clinical Supply Management and Forecasting

Download the eBook to explore a proactive approach for clinical supply management.

Events