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October 25, 2019___

Today's Rundown

Featured Story

Gilead’s filgotinib fails midphase tests in lupus, Sjogren's

A clutch of Gilead drugs including filgotinib have failed to move the needle in midphase clinical trials of cutaneous lupus and Sjogren's syndrome patients. Neither trial hit the primary endpoint, although Gilead did see “evidence of activity” in patients taking filgotinib.

Top Stories

Kronos Bio nabs Gilead, Baylor College of Medicine researchers

Fierce 15 winner Kronos Bio has hired two new research program execs as it looks to put its recent funding haul to work.

Syros links SY-1425 combo to 50%-plus AML complete response rate

Syros Pharmaceuticals has posted updated clinical data on SY-1425 in acute myeloid leukemia (AML). Seven of the 13 newly diagnosed AML patients with a certain biomarker had full complete responses after receiving the RARα agonist in combination with Celgene’s Vidaza. 

[Sponsored] Advancing Site-Sponsor Relationships

Clinical trials involve massive complexity and, often, systems that lack consistency and discipline. With a new perspective to an old problem, WCG coordinates the execution of six proven strategies to dramatically and consistently bring clinical studies to launch faster and at a lower cost.

U.K. team sheds light on how AnaptysBio's anti-IL-33 eczema drug tamps down inflammation

AnaptysBio's etokimab, which targets IL-33, works by altering how immune cells that cause inflammation respond to allergens, researchers discovered by testing the skin of patients in a phase 2 trial.

EuroBiotech Report—UCB beats J&J, Novartis fail, AstraZeneca, NASH deal and Evotec

In this week's EuroBiotech Report, UCB's bispecific beats J&J's Stelara, AstraZeneca dumps phase 3 cancer program and Novartis fails pivotal test.

FiercePharmaAsia—Novartis’ generics deal, Zolgensma decision delays; AZ’s China performance

Sandoz's $1 billion U.S. generics deal with India's Aurobindo Pharma is delayed by FTC review. Decisions for Novartis' Zolgensma in EU and Japan are pushed back due to manufacturing questions. AstraZeneca expects mid-teens sales growth from China in the mid-term. And more.

Chutes & Ladders—Eli Lilly diabetes head Conterno set to step down

Eli Lilly diabetes chief Conterno will step down; MD Anderson's Hahn likely pick for FDA head; Amgen CFO Meline bows out.

Resources

[Article] 8 Compelling Reasons Why Businesses Need To Be In The Cloud Now!

Companies that don’t have a cloud strategy are at a competitive disadvantage. Why? The cloud has a measurable impact on business.

[Whitepaper] The Next Generation of Trial Master File Systems

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[Whitepaper] Cortellis Q2 2019 M&A report

Download this report for full details of Life sciences M&As in the second quarter of 2019 with notes and trends.

[Whitepaper] SOAR™ Model Manages Data From Source to Submission

Find out how it leverages real-world data and novel IntElligo Research Stack™ technology to help researchers battle rising costs, cumbersome processes, and stagnant participation — bridging the gap between research and care.

[Whitepaper] Successful Clinical Trials in the Era of Genetics-based Medicine

Download this complimentary guide paper that explores key strategies for a successful genetics-informed clinical trial.

[Whitepaper] Best Practices for Incorporating Real World Imaging Data into RWE Programs

The time has finally come when medical imaging can be effectively utilized into the RWE process. Read the whitepaper on the best practices for incorporating Real World Imaging.™

[Whitepaper] Synthesizing Success: Six Principles for Getting Pharmaceutical Development Right from the Start

Is your API development on track?

[Whitepaper] Webinar Benchmarks Report for Life Sciences 2019

Compare digital program performance and audience engagement among your life sciences peers.

[Webinar] Clinically Integrated Networks: A Growing Disruptor in American Healthcare

Clinically Integrated Networks are vehicles for powerful IDNs to extend their influence into the physician sector and play a key role for IDNs trying to pave a path to becoming a self-contained healthcare ecosystem.

[Whitepaper] Innovative Funding Models for Treatment of Cancer and Other High-Cost Chronic Noncommunicable Diseases

A global landscape study of funding trends and innovations.

[Case Study] Clinical Supply Management

Download the case study to learn about the clinical supply management tools that helped a small sized pharma company during phase III of a multi-arm oncology study.

[Video] Demand Led Services and Clinical Supply Efficiency

Watch a short video on demand led supply model. It is designed to meet the needs of patients, clinical sites, clinical team and sponsors and results in shorter lead time, less waste, less stock out risk and no booklet labels.

[eBook] Strategies for Efficient Clinical Supply Management and Forecasting

Download the eBook to explore a proactive approach for clinical supply management.

Events