Regeneron hit by 'safety signal' for COVID-19 cocktail as data board tells pharma to stop enrolling sicker patients Bellicum shares nose-dive on poor CAR-T data, program pause—company axes 79% of staffers Novo Nordisk scraps Type 1 diabetes drug after phase 2 trial Astellas cuts Potenza anti-TIGIT asset in quarterly cull SQZ Biotech, breaking convention, hits the NYSE with $71M IPO Golumbeski, Hasnain join Vertex Ventures as executive advisers C2N debuts Alzheimer's blood test for predicting amyloid plaque deposits in the brain Training the innate immune system to fight cancer FiercePharmaAsia—Takeda-Moderna COVID vaccine deal; CStone-EQRx PD-1/L1 pact; Korea flu shot woe Chutes & Ladders—Bayer adds Roche veteran Rommel as research head Featured Story | By Ben Adams The saga of COVID-19 antibody R&D continues as the REGN-COV2 antibody cocktail used by President Donald Trump and touted as a cure has been hit by safety worries as it continues to push for an FDA emergency authorization. read more |
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Top Stories By Ben Adams Bellicum’s shares are being routed after it announced a full house of horrors: poor data, a paused program and slashing the vast majority of its staff as it looks to save cash. read more By Nick Paul Taylor Novo Nordisk has scrapped development of anti-IL-21 antibody NN9828 in combination with Victoza after getting a look at phase 2 data in Type 1 diabetics. The news is another setback for a drug that has underwhelmed in multiple indications over the past decade. read more By Ben Adams In 2018, Astellas spent $405 million to buy out long-term biotech partner Potenza and its small group of early-stage cancer drugs. read more By Amirah Al Idrus When it’s time to go public, most biotech companies for the Nasdaq. Not so for cell therapy-focused SQZ Biotech, which raised $71 million in its New York Stock Exchange debut. The proceeds will bankroll a pipeline of cell therapies based on a platform that squeezes cells through a microfluidic chip, disrupting their membranes to get materials into them. read more By Nick Paul Taylor Vertex Ventures has named George Golumbeski and Faheem Hasnain as executive advisers. The appointments position the VC fund to benefit from the input of industry veterans who, respectively, turned Celgene into one of the most active deal-makers in biotech and ran companies including Receptos. read more By Conor Hale C2N Diagnostics is launching a simple blood test the company says can identify the state of amyloid plaque in the brain, one of the hallmarks of the neurodegenerative condition. read more By Angus Liu Existing immuno-oncology therapies primarily leverage adaptive immunity to fight cancer. A research team led by scientists at the Icahn School of Medicine at Mount Sinai has discovered a possible way to tap the innate immune system, using a nanobiologic to boost the effectiveness of checkpoint inhibitors in mice. read more By Angus Liu Takeda has inked a deal to help bring Moderna's COVID-19 vaccine to Japan. China's CStone Pharmaceuticals out-licensed its PD-1 and PD-L1 inhibitors to EQRx in a potential $1.3 billion deal. Singapore halted two flu shots amid rising post-vaccination deaths in Korea. And more. read more By Kyle Blankenship Roche veteran Rommel joins Bayer as head of research; Cogent names Robbins as CEO; Fox takes over CFO role at Nuvation. read more Resources Sponsored By: Paysign In this case study on the Alec Smith Insulin Affordability Act, you will learn not just about the law but about the portal platform designed to change the entire process for manufacturers, pharmacists, and patients.
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