Bos Sci’s TAVR fails head-to-head study

Today’s Big News

Oct 30, 2024

Eli Lilly rolls the dice, axing psoriasis prospect and pivoting to follow-up 1 year after $2.4B buyout


AbbVie's Skyrizi snatches sales crown from Humira as company lifts full-year profit guidance


Biogen boosts profit guidance despite modest quarter for Leqembi and multiple sclerosis downturn


TCT 2024: Valve under-expansion plagues Boston Scientific’s head-to-head TAVR trial


GSK axes vaccine from $2.1B deal, switching to preclinical successor over 'increased competition'


AstraZeneca's China president faces 'ongoing investigation' by authorities in the country


TCT 2024: J&J’s Abiomed clears pivotal study for shrinkable heart pump

 

Featured

Eli Lilly rolls the dice, axing psoriasis prospect and pivoting to follow-up 1 year after $2.4B buyout

Eli Lilly has dropped the lead candidate from its $2.4 billion takeover of Dice Therapeutics, shifting the focus of its oral IL-17 psoriasis program to a follow-up molecule. Lilly kicked DC-806 to the curb as part of a third-quarter cull that also affected the PD-1 autoimmune prospect peresolimab.
 

Top Stories

AbbVie's Skyrizi snatches sales crown from Humira as company lifts full-year profit guidance

After several quarters of creeping up on Humira, Skyrizi is now on top for the Illinois pharma giant. This year, AbbVie's Humira successors are expected to bring in revenues of $17 billion.

Biogen boosts profit guidance despite modest quarter for Leqembi and multiple sclerosis downturn

All told, third-quarter U.S. Leqembi sales grew 33% over the prior quarter to $39 million, falling short of consensus estimates. But behind the scenes, there was a 40% uptick in the number of new prescribers writing prescriptions for Leqembi in the third quarter versus Q2, Alicia Alaimo, Biogen’s president and head of North America, said Wednesday.

TCT 2024: Valve under-expansion plagues Boston Scientific’s head-to-head TAVR trial

Boston Scientific’s long-awaited Acurate neo2 transcatheter aortic heart valve missed its mark in a study aimed at bringing it to the U.S.—but the company believes it has a fix.

GSK axes vaccine from $2.1B deal, switching to preclinical successor over 'increased competition'

GSK has stopped development of one of the lead programs from its $2.1 billion Affinivax takeover, axing a phase 2 pneumococcal 24-valent vaccine candidate for adults in favor of a preclinical 30-plus valent shot. A spokesperson for GSK said “increased competition” drove the decision.

AstraZeneca's China president faces 'ongoing investigation' by authorities in the country

Following a report of an ex-AstraZeneca executive being detained in China, the company acknowledged that its current president in the country, Leon Wang, "is cooperating with an ongoing investigation."

TCT 2024: J&J’s Abiomed clears pivotal study for shrinkable heart pump

The Impella ECP is a redesign of the 12-year-old Impella CP, with a structure that lets it to compress to a smaller diameter as it enters the body and navigates the blood vessels.

Roche sees rapid amyloid clearing in Alzheimer’s study, adjusts protocol after patient death

Early data suggest Roche’s antibody may safely and quickly remove amyloid plaque for patients with Alzheimer’s disease, though the mid-stage study has been tied to one death.

Almirall celebrates inner circles that help patients, making friends and family its focus for psoriasis day

Almirall has put patients’ friends and family at the heart of its activities for the 2024 World Psoriasis Day, launching the “Me & My Inner Circle” campaign to celebrate communities that help people living with the skin condition.

Sage discontinues Zulresso, drops pair of pipeline prospects as it creeps toward 2026 cash cliff

In the wake of a recent round of layoffs, the company this week revealed that it’s discontinuing a commercial medicine and giving up hopes for a pair of pipeline prospects.

Fierce Biotech Layoff Tracker 2024: Spero lays off 39% of workforce; Pfizer lays off 75 more workers in NC

We really didn't want to have to create another Layoff Tracker this year. But here we are, launching the third annual iteration tracking biopharma layoffs. 
 
Fierce podcasts

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'The Top Line': The pulse of the medtech industry

This week on "The Top Line," Fierce Medtech's Conor Hale dives into EY's 18th annual Pulse of the MedTech Industry report and chats with EY's John Babbitt about the team's findings and the pace of M&A, venture capital funding and recent IPOs. 

 

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Communicating the Value of Biopharma Assets to Potential Investors

How can an emerging company attract the right partner for a therapeutic asset (& optimize its value in a transaction)? This paper offers some insights.
 

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On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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