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October 31, 2019___

Today's Rundown

Featured Story

Roche pays $200M for rights to Dicerna's hepatitis B RNAi drug

Roche is paying Dicerna Pharmaceuticals $200 million (€179 million) upfront for a global license to phase 1 hepatitis B prospect DCR-HBVS. The deal, which will see Roche and Dicerna collaborate on other hepatitis B virus assets, is worth up to $1.5 billion in milestones.

Top Stories

Sanofi axes cancer combo, early next-gen diabetes drug

If you’ve been paying attention this week, you’ve seen that nearly every Big Pharma has been sweeping out dead R&D projects: Sanofi, posting its third-quarter results early this morning, is no different.

Andreessen Horowitz leads $75M round for Tmunity as it eyes phase 2 studies for 2021

In January, Tmunity Therapeutics laid out an “aggressive” plan to unveil new targets, move programs into the clinic and boost its headcount. As it delivers on some of those goals, the cell therapy biotech is coming back to the well for a $75 million series B that will take it into phase 2 studies in 2021.

[Sponsored] RenMab™ Mouse: a leading platform for fully human antibody generation

Biocytogen uses chromosome engineering for the in situ replacement of mouse antibody genes with the human counterparts, authentic position within the chromosome.

Astellas, Pandion team up on Type 1 diabetes bispecifics in deal worth up to $795M

As Pandion Therapeutics preps its lead program for the clinic, the autoimmune specialist is giving its earlier-stage pipeline a boost. It is teaming up with Astellas Pharma to discover, develop and market bispecific drugs for Type 1 diabetes and other autoimmune diseases of the pancreas in a deal that could total nearly $800 million.

Ex-Pfizer team leads Pinteon into phase 1 Alzheimer's trial

Pinteon Therapeutics has begun a phase 1 trial of an anti-tau treatment for Alzheimer’s disease. Led by ex-Pfizer scientists, Pinteon is using $17 million in series A funding to assess the safety, tolerability and pharmacokinetics of lead asset PNT001.

Medtronic launches brain-stim programmer on a Samsung phone

Medtronic has launched a new system that allows patients to manage their deep brain stimulation treatments at home using a dedicated and customized Samsung smartphone.

Resources

[Infographic] Implement the Patient Voice to Build an Effective Engagement App

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[eBook] Customer Experience: Shaping Digital Healthcare

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[Whitepaper] How to succeed by failing faster

This white paper examines the skyrocketing cost of drug development and provides step-by-step guidance for executing a successful fail fast strategy.

[Article] 8 Compelling Reasons Why Businesses Need To Be In The Cloud Now!

Companies that don’t have a cloud strategy are at a competitive disadvantage. Why? The cloud has a measurable impact on business.

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[Whitepaper] SOAR™ Model Manages Data From Source to Submission

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[Whitepaper] Successful Clinical Trials in the Era of Genetics-based Medicine

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[Whitepaper] Synthesizing Success: Six Principles for Getting Pharmaceutical Development Right from the Start

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[Whitepaper] Innovative Funding Models for Treatment of Cancer and Other High-Cost Chronic Noncommunicable Diseases

A global landscape study of funding trends and innovations.

[Case Study] Clinical Supply Management

Download the case study to learn about the clinical supply management tools that helped a small sized pharma company during phase III of a multi-arm oncology study.

[Video] Demand Led Services and Clinical Supply Efficiency

Watch a short video on demand led supply model. It is designed to meet the needs of patients, clinical sites, clinical team and sponsors and results in shorter lead time, less waste, less stock out risk and no booklet labels.

[eBook] Strategies for Efficient Clinical Supply Management and Forecasting

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Events