To view this email as a web page, click here

Subscribe

Advertise

 

 

 

 

 

 

November 08, 2019

It’s a tough job, and arguably just as important as the CEO: for the multinationals that rely on science and innovation, the top R&D executives in biopharma can bring home quite the pay package. You’d think salaries would track with the size of companies’ research budgets, but that’s not always the case—Regeneron’s George Yancopoulos tops our list, even though his company’s R&D spend doesn’t break the top 10. For more eye-watering paychecks and other surprises, as well as a microcosm of biopharma’s R&D world and this week’s top stories, read on below.

Featured Story

Special Report—The top 10 highest paid biopharma R&D executives in 2018

The top research and development executives from across biopharma are certainly not looking down the back of the sofa for change; most are earning around $7 million a year. But then the job is tough, and arguably just as important as the top CEO job, given how much companies rely on the strength of their R&D.

Top Stories Of The Week

Pfizer's early Vyndaqel launch numbers are off the charts. Should Alnylam be worried?

Thanks to Pfizer's marketing push, diagnosis of the rare heart disease ATTR cardiomyopathy is on the rise—and its Vyndaqel treatment is zooming ahead. The med hauled in $156 million in the third quarter, way ahead of expectations, putting more pressure on Alnylam's Onpattro.

Novo drops oral GLP-1 analog to focus on next-gen Rybelsus

Novo Nordisk has stopped development of its next-generation oral GLP-1 analog OG2023SC. The Danish drugmaker took the action after making progress with an enhanced version of its existing oral semaglutide formulation.

Stryker to buy orthopedic device maker Wright Medical for $4B

Stryker is moving to acquire fellow devicemaker Wright Medical in a $4 billion play to gain a stronger foothold in fast-growing orthopedic segments.

Novartis' Cosentyx can't top AbbVie's Humira in head-to-head psoriatic arthritis contest

Eli Lilly’s Taltz and Novartis’ Cosentyx have been battling it out lately in the next-gen psoriatic arthritis field. But Lilly’s drug has a big win under its belt that Novartis can’t tout. Cosentyx failed to outdo AbbVie behemoth Humira in a head-to-head trial in active psoriatic arthritis patients.

FDA: Zantac carcinogens no more dangerous than 'grilled or smoked meats'

With global recalls of heart burn med Zantac ongoing, the FDA is hoping to restore consumer confidence. Worried about higher-than-recommended levels of a possible carcinogen in the pills? They're no more dangerous than a grilled ribeye, the agency said Monday. 

Daiichi sues Seattle Genetics over tech used in high-profile ADC

Daiichi Sankyo has started legal action against Seattle Genetics. The case centers on linker technology used in antibody-drug conjugates (ADCs) including Daiichi’s AstraZeneca-partnered DS-8201.

Halozyme kills pipeline, cuts 55% of jobs as lead cancer med flops in phase 3

Until today, Halozyme worked under a two-pillar strategy, with licensing dollars from its Enhanze drug delivery technology bankrolling its cancer pipeline. Now, with the failure of its lead program in pancreatic cancer, the company is pulling the plug on drug development to focus solely on Enhanze and cutting 55% of its staff in the process.

Think Mylan's done with M&A after its Pfizer deal? Think again

Mylan is focused on closing its merger with Pfizer's Upjohn next year. But after that deal closes, the pumped-up company should have the firepower for more M&A deals, an exec said. Meanwhile, the company canned 350 products in a cleanout of its current portfolio.

Aurobindo is finding it difficult to satisfy the FDA, FTC

India’s Aurobindo, which has yet to meet FTC terms to complete a $1 billion deal to buy a significant chunk of Sandoz U.S. generics business, also continues to struggle to meet FDA terms for its manufacturing plants.

Gene therapy to fend off aging? Buzzy Harvard startup Rejuvenate Bio says it works in mice

Harvard synthetic biology pioneer George Church generated some buzz last year when he co-founded Rejuvenate Bio with the goal of reversing aging with gene therapy. Now, he and his co-founders say they have compelling early evidence in mice that they can use the technology to relieve or reverse Type 2 diabetes, obesity, and heart and kidney failure.

Enrollment Showcase

A Credential for the Future of Health Care

Join the future of health care with the flexibility and convenience of an online program.

Resources

[Whitepaper] Medical Affairs 2025 Excellence in the Era of Precision Medicine

Medical Affairs 2025 brings together leading perspectives from AstraZeneca, Bristol-Myers Squibb, Merck, Lilly, and other innovative life sciences organizations on key challenges impacting medical affairs and a roadmap for success in the coming decade.

[Whitepaper] The State of Real-World Evidence in Biopharma

This whitepaper provides a snapshot of where the biopharma industry is now, where it's heading, and how companies are allocating their resources to adapt & grow.

[Whitepaper] The importance of early key opinion leader outreach in the biologics and biosimilars marketplace

Acknowledging various stakeholder networks, as well as recognizing variances within the regulatory environment, we believe, is essential for companies looking to uncover the right decision-makers in support of biologics or biosimilars. Learn more.

[Whitepaper] 5 Best Practices for Marketing Medical Devices

Discover solutions to the most common challenges faced by medical device companies.

[Whitepaper] The Impact of Step-Therapy Policies on Patients

Download this complimentary paper that explores the practice of step therapy and its impact on key stakeholders in the US healthcare system.

[Whitepaper] Q2 2019 Biopharma licensing report

18 high-value new licensing deals worth in excess of $500 million took place during the second quarter of 2019 -Get the Q2 2019 Biopharma licensing report for full details and insights.

[Whitepaper] Synthesizing Success: Six Principles For Getting Pharmaceutical Development Right From The Start

Is your API development on track?

[Infographic] Implement the Patient Voice to Build an Effective Engagement App

Get the latest data on how people are using apps to manage their health, and learn how you can leverage it in the development of your next clinical trial app.

[eBook] Customer Experience: Shaping Digital Healthcare

Report: How to design digital services that deliver value and improve outcomes for patients, healthcare professionals and the healthcare systems they serve

[Whitepaper] How to succeed by failing faster

This white paper examines the skyrocketing cost of drug development and provides step-by-step guidance for executing a successful fail fast strategy.

[Whitepaper] Implementing On-Dose Authentication Technologies for Solid Dose Drug Products

Learn about how you better manage product authentication and battle drug counterfeiting with innovative solutions.

[Whitepaper] Innovative Funding Models for Treatment of Cancer and Other High-Cost Chronic Noncommunicable Diseases

A global landscape study of funding trends and innovations.

[Case Study] Clinical Supply Management

Download the case study to learn about the clinical supply management tools that helped a small sized pharma company during phase III of a multi-arm oncology study.

[Video] Demand Led Services and Clinical Supply Efficiency

Watch a short video on demand led supply model. It is designed to meet the needs of patients, clinical sites, clinical team and sponsors and results in shorter lead time, less waste, less stock out risk and no booklet labels.

[eBook] Strategies for Efficient Clinical Supply Management and Forecasting

Download the eBook to explore a proactive approach for clinical supply management.