Jazz drums up $771M Autifony pact

Today’s Big News

Nov 14, 2023

Pfizer's cost-cutting campaign hits Sandwich site in the UK, where 500 workers will lose jobs


Hepatitis B drug developers chart slow progress forward, just like hep C before it


Vicarious lays off a swath of R&D workers, delays timeline on surgical robot development


Jazz locks arms with GSK spinout Autifony, putting up $771M to form neuroscience discovery pact 


Merck KGaA's pharma unit joins the healthcare migration to Boston's Seaport innovation hub

 

Featured

Pfizer's cost-cutting campaign hits Sandwich site in UK, where 500 workers will lose jobs

Pfizer plans to cut approximately 500 roles and ax its Pharmaceutical Sciences Small Molecule capabilities at its site in Sandwich in Kent in the U.K. The move is a consequence of Pfizer’s enterprisewide cost realignment program, which the drugmaker unveiled in mid-October.
 

Top Stories

Hepatitis B drug developers chart slow progress forward, just like hep C before it

Developing a functional cure for hepatitis B has proved elusive, with the pipeline of new clinical therapies incrementally growing in the last seven years. More midstage readouts and a handful of new deals are adding much-needed optimism that progress is being made.

Vicarious lays off a swath of R&D workers, delays timeline on surgical robot development

Unfortunately for Vicarious Surgical, the robotic surgery system developer is ending the year the same way it began: with a round of layoffs.

Jazz locks arms with GSK spinout Autifony, putting up $771M to form neuroscience discovery pact

GSK spinout Autifony Therapeutics has drummed up a collaboration with Jazz Pharmaceuticals, securing up to $770.5 million to discover and develop drug candidates against two ion channel targets associated with neurological disorders.

Merck KGaA's pharma unit joins the healthcare migration to Boston's Seaport innovation hub

Add another to the list of healthcare companies joining Boston's transformed Seaport district, as Merck KGaA's pharma subsidiary, EMD Serono, said it will move its U.S. headquarters from 25 miles south in Rockland to Seaport.

AstraZeneca’s Imfinzi regimen misses the mark in setback for ambitious lung cancer 2030 goal

One study in AstraZeneca’s elaborate R&D plan for lung cancer has reached a dead end. Failure of the Imfinzi-concurrent-chemoradiotherapy regimen deals a blow to AZ’s goal to target more than half of lung cancer patients by 2030.

Eko’s AI-paired stethoscopes catch heart murmurs at double the rate of analog devices, study finds

Just a few months after the official U.S. launch of its Sensora platform, Eko Health has published a study detailing the real-world performance of the platform’s first artificial intelligence-powered heart disease detection tool.

Telix offers $33M to acquire Qsam for phase 1 bone cancer radiopharmaceutical

Telix Pharmaceuticals has offered to pay $33.1 million for Qsam Biosciences so the Australian biotech can get its hands on a phase 1 radiopharmaceutical for bone cancer.

Stagnant sales for Dermavant's Vtama cast doubt on its blockbuster potential

In the clinic, Dermavant’s Vtama is progressing nicely as trial results have paved the way for it to be approved for atopic dermatitis (eczema) on top of its current indication for plaque psoriasis. In the market, however, Vtama is struggling to catch on. As a result, Leerink Partners has slashed its sales projections for the nonsteroidal topical treatment.
 
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Psychedelics and the next frontier of mental healthcare

In this episode of “The Top Line,” we explore the next potential wave of mental health therapy: psychedelics.

 

Resources

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This paper explores AI’s potential impact on healthcare and on Medical Affairs (MA) more specifically. It also outlines what MA teams can do now to proactively leverage AI to improve service to their stakeholders.
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An Introduction to Organ-on-a-Chip Technology

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Accelerate drug discovery with high-performance computing powered by the cloud

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