Graphite ends gene editing mission with merger

Today’s Big News

Nov 15, 2023

Regeneron stays out of ADC deal fray as in-house scientists tinker


Organon CEO: ‘We are definitely going to be involved’ with White House women’s health initiative 


Pencils down for Graphite, as gene editing biotech merges into vision loss-focused LENZ


Gilead hands Arcellx $285M to expand BCMA cell therapy deal, sparking fresh push for congested market


Mural Oncology wants to paint a new picture in IL-2 after Alkermes spinout


Atreca, facing Q1 funding cliff edge, cuts head count by 40% for 2nd time in 3 months


Fierce Biotech Fundraising Tracker '23: NMD Pharma nabs $81M for neuromuscular diseases; T-Therapeutics takes home $59M

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

Regeneron stays out of ADC deal fray as in-house scientists tinker

Regeneron is pretty good at making antibodies. It’s kind of its thing. But while the industry has gone crazy for antibody-drug conjugates, the company has stayed out of the limelight.
 

Top Stories

Organon CEO: 'We are definitely going to be involved' with White House women's health initiative

Organon CEO Kevin Ali says that while it wasn't involved in the recent women's health initiative announced by the White House, it plans to be moving forward.

Pencils down for Graphite, as gene editing biotech merges into vision-loss-focused Lenz

Lenz Therapeutics is absorbing sickle-cell-focused Graphite Bio in a reverse merger that will see the combined company reemerge with a focus on vision loss and $225 million in cash on hand at close.

2023 Executive Interviews at Fierce Biotech Summit and New Product Planning

Fierce Biotech sits down with digital marketing leaders to discuss this year's most innovative topics at Fierce Biotech Summit and New Product Planning

Gilead hands Arcellx $285M to expand BCMA cell therapy deal, sparking fresh push for congested market

Gilead’s Kite is paying Arcellx $285 million to inject a SparX into its pursuit of BCMA. In return for the outlay, $200 million of which is being invested in Arcellx, Kite has secured rights to an early-phase BCMA CAR-T candidate and expanded its existing midphase cell therapy collaboration to cover lymphomas. 

Mural Oncology wants to paint a new picture in IL-2 after Alkermes spinout

Mural Oncology, Alkermes’ cancer spinoff, has officially landed with $275 million in funding and a mission to develop an IL-2 candidate for solid tumors.

Atreca, facing Q1 funding cliff edge, cuts head count by 40% for 2nd time in 3 months

Atreca is handing out pink slips at a furious rate in a fight to survive, reducing its head count by 40% for the second time in three months in a bid to keep the lights on until strategic alternatives can be identified.

Fierce Biotech Fundraising Tracker '23: NMD Pharma nabs $81M for neuromuscular diseases; T-Therapeutics takes home $59M

Alongside the new year, we've launched a new Fierce Biotech Fundraising Tracker to keep the pulse on the industry's financing.

Novo Nordisk fights back at Lilly with Wegovy combo trial against Zepbound in obesity

In response to an onslaught from Eli Lilly, Novo Nordisk is escalating the obesity market battle with a new head-to-head trial against its archrival.

FDA's oncology office uses advisory committee to spotlight timely accelerated approval confirmation

An upcoming meeting of the FDA’s oncologic drugs advisory committee is slated to serve as a reminder for cancer drug developers that the agency is keeping a close eye on accelerated approvals.

Vicarious lays off a swath of R&D workers, delays timeline on surgical robot development

Unfortunately for Vicarious Surgical, the robotic surgery system developer is ending the year the same way it began: with a round of layoffs.

Primary care player Forward unveils AI-based, self-serve CarePods backed by $100M series E round

Primary care player Forward unveiled this week what it has been quietly working on the past two years—self-serve CarePods that use artificial intelligence to screen and diagnose health conditions.
 
Fierce podcasts

Don’t miss an episode

'Podnosis': A deep dive into Q3 earnings, and key takeaways from the Fierce Health Payer Summit

In this week’s episode of "Podnosis," you'll hear from two journalists from the Fierce Healthcare team: Paige Minemyer, senior editor of Fierce Health Payer, and Dave Muoio, a staff writer for Fierce Healthcare. Together, they guide you through their key insights from the inaugural Fierce Health Payer Summit in Austin and dive into the latest earnings updates from the largest health plans and health systems.
 

Resources

Whitepaper

Effective Technology Transfers for Mammalian-Derived Biologics

As a leader of technology transfer activities in the industry, Lonza understands the challenges associated with this critical step. Download this White Paper today to learn more. 

Webinar

Reimagine the infrastructure that makes science possible

Watch now to explore the convergence of science, capital, operational excellence and workplace strategy.
Whitepaper

Overcome Challenges and Secure Successful Technology Transfers of Complex Biological Products in Sterile Manufacturing

A critical area to consider in selecting a CDMO is their ability to successfully complete technology transfers, which involves an intricate set of activities and disciplines that, if done incorrectly, could result in delays and failures that impact the overall success of your end product. Recognizing what it takes to complete this process effectively and efficiently is crucial to selecting the best partner for your project and product needs. This white paper delivers an analysis of critical success factors for effective technology transfer.
Whitepaper

Enhance the cost-effectiveness of your GMP chemical supply chain

Learn how to develop a high-performing supply chain for cGMP chemicals used throughout your bioprocessing workflows.
Whitepaper

Plasmid DNA Design Considerations for Cell and Gene Therapy

Download our whitepaper to learn about plasmid DNA design considerations for cell and gene therapy applications.
Whitepaper

Artificial Intelligence in Healthcare & Medical Affairs

This paper explores AI’s potential impact on healthcare and on Medical Affairs (MA) more specifically. It also outlines what MA teams can do now to proactively leverage AI to improve service to their stakeholders.
eBook

An Introduction to Organ-on-a-Chip Technology

Emulate in vivo biology with next-generation in vitro technology.
Whitepaper

Accelerate drug discovery with high-performance computing powered by the cloud

Accelerate drug discovery with high-performance computing (HPC) powered by the cloud
 

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