Plus, 2024’s Fiercest Women in Life Sciences

Editor's Note: Fierce Life Sci’s weekly digest will not publish next week, in observance of the U.S. Thanksgiving holiday. We’ll be back in your inboxes December 6.

This Week

Nov 22, 2024

Amid Seattle downsizing, Gilead cuts 100+ positions at California HQ 


Pfizer plucks internal candidate to replace R&D head Dolsten, triggering series of leadership shakeups


SPECIAL REPORT—2024's Fiercest Women in Life Sciences 


CSL Behring shuts down California cell and gene therapy R&D site amid group pivot


Johnson & Johnson, Merck lay off workers in China as local headwinds take a toll


Vaccine stocks sag in US, Europe after RFK Jr.'s HHS appointment 

 

Featured

2024's Fiercest Women in Life Sciences

Despite lingering barriers to equity, women continue to do incredible, groundbreaking work throughout pharma, biotech and medtech. As seen in the following profiles of 10 of the fiercest women in life sciences, they’re spearheading Big Pharma business development, guiding up-and-coming biotechs and leading clinical research into potentially lifesaving technologies and therapeutics.
 

Top Stories

Amid Seattle downsizing, Gilead cuts 100+ positions at California HQ

The scope of Gilead Sciences' recent round of layoffs is coming into clearer view with the revelation that the company is planning more than 100 cuts at its corporate headquarters.

Pfizer plucks internal candidate to replace R&D head Dolsten, triggering series of leadership shakeups

Pfizer has found a successor for Chief Scientific Officer and R&D head Mikael Dolsten, M.D., Ph.D., tapping the company’s own Chris Boshoff, M.D., Ph.D., for the job and prompting a domino-effect of leadership changes.

CSL Behring shuts down California cell and gene therapy R&D site amid group pivot

CSL Behring is shutting down its U.S. R&D hub for cell and gene therapy in Pasadena, California, Fierce Biotech has learned.

Johnson & Johnson, Merck lay off workers in China as local headwinds take a toll

Johnson & Johnson and Merck are laying off workers in China, according to a story from Bloomberg which cites reports from Chinese news outlets.

Vaccine stocks sag in US, Europe after RFK Jr.'s HHS appointment

President-elect Donald Trump's choice for HHS secretary could pose risk to vaccine makers' top lines, as evidenced by sinking share prices after the appointment.

Halozyme offers $2B for Evotec to expand beyond delivery tech used by J&J and Roche

Halozyme Therapeutics has bid to buy Evotec for around 2 billion euros ($2.1 billion). Evotec confirmed it received an offer and said it is analyzing the proposal before deciding on the next steps.

Innate Pharma antibody pits natural killer cells against cancerous B cells in mice and monkeys

French biotech Innate Pharma is recruiting natural-born killers to target B cell non-Hodgkin lymphoma. The company’s tetraspecific antibody controlled tumors and improved survival in mice and reduced cancerous B cells in cynomolgus macaques.

Cleanup for the IL-23 class in ulcerative colitis as new drugs 'rapidly gained significant momentum': report

The new ulcerative colitis (UC) triumvirate in Johnson & Johnson’s Tremfya, AbbVie’s Skyrizi and Lilly’s Omvoh is rapidly growing into the established UC market as this IL-23 inhibitor class of drugs look to make its mark.

Medtronic sees pulsed field ablation cut into cryo sales amid supply issues

Medtronic has reported revenue gains across several of its medical device franchises, leading the company to nudge up its financial guidance for the remainder of the year.

FDA slams Indian drugmaker Unexo with warning letter for 'significant violations'

Unexo Life Sciences, an Indian drugmaker that manufactures a medicated patch for pain relief, has been hit with a warning letter from the FDA.
 
Fierce podcasts

Don’t miss an episode

An emerging cyberthreat: vishing

This week on "Podnosis," we explore the rise of voice phishing, or vishing, where cybercriminals use AI to mimic voices and breach sensitive healthcare data.
 

Resources

Whitepaper

Single Cell RNA Profiling FFPE Tissue

Explore the robust cross-platform agreement between scRNA-seq and bulk RNA-seq, ensuring consistent and reproducible data on immune cell presence.
Whitepaper

Straight to Market in an Autoinjector

The use of prefilled syringes to administer biotherapeutics is beginning to gain traction because they offer a range of stability, efficacy, and patient safety benefits. Download this white paper to learn how Lonza has developed a novel workflow to ensure confidence regarding functionality in PFS and autoinjectors.
Whitepaper

Industry Insights: What to Expect from a 3PL

Selecting a 3PL with a proven track record of delivering high-quality services is critical to a successful pharma supply chain. Here's how.
Whitepaper

7 “Make or Break” Factors for Emerging Biopharma Companies

This e-book explores 7 factors that are critical to the success of emerging biopharma companies, whether they plan to out-license, partner, or launch & commercialize products. It’s an essential resource for emerging companies with products in all stages of development.
Whitepaper

Intensified Biomanufacturing

Unlock the secrets to faster, cost-effective biologics production with intensified biomanufacturing – download the whitepaper and power up your bioprocessing game!
Whitepaper

Direct-To-Patient Cash Solutions for Pharma Manufacturers

Direct-To-Patient Cash Solutions for Pharma Manufacturers – learn how to leverage cash models strategically to mitigate access challenges and overcome the hurdles faced in today’s retail pharmacy environment.
Whitepaper

Planning for success in cell-based manufacturing

Learn how to evaluate quality documentation to help you select the right raw materials at early decision points for your cell-based manufacturing processes.
 

Industry Events

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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