Illumina previews updated tumor research assay

Today’s Big News

Nov 22, 2024

Halozyme withdraws $2B bid for Evotec after German biotech was 'unwilling to engage'


After FDA setbacks, Lexicon slashes commercial operations in transition back to clinical-stage outfit


Illumina previews updated tumor research assay, begins shipping IVD kits


Neurogene reports death of Rett patient left in critical condition by high dose of gene therapy


Meet 2024’s fiercest women in life sciences


Chutes & Ladders—Pfizer replaces retiring CSO with cancer chief

 

Featured

Halozyme withdraws $2B bid for Evotec after German biotech was 'unwilling to engage'

Halozyme Therapeutics has withdrawn its $2.1 billion offer to buy Evotec after the German company “has been unwilling to engage with us to explore a potential combination,” Halozyme president and CEO Helen Torley said in a Nov. 22 release.
 

Top Stories

After FDA setbacks, Lexicon slashes commercial operations in transition back to clinical-stage outfit

The pivot comes after the FDA issued a notice that the deficiencies in the company's approval bid for type 1 diabetes med Zynquista are too great to proceed for further discussion.

Illumina previews updated tumor research assay, begins shipping IVD kits

Version 2 of the TruSight Oncology 500 tissue research-use-only assay is currently under development, the company said, with a global release set for mid-2025.

Neurogene reports death of Rett patient left in critical condition by high dose of gene therapy

A patient has died after receiving the high dose of Neurogene’s Rett syndrome gene therapy candidate. The biotech previously reported that the patient was in critical condition.

Meet 2024’s fiercest women in life sciences

This week on "The Top Line," Fierce editors discuss our special report celebrating 10 women driving change in clinical research, business development, venture capital, and more

Chutes & Ladders—Pfizer replaces retiring CSO with cancer chief

Pfizer has found a successor for retiring Chief Scientific Officer and R&D head Mikael Dolsten, M.D., Ph.D., tapping the company’s own Chris Boshoff, M.D., Ph.D., for the job and prompting a domino effect of leadership changes.

As other Big Pharmas face local headwinds, Pfizer doubles down on China commitment with Zai Lab antimicrobial marketing pact

Pfizer has been tapped by Shanghai-based Zai Lab to help market the company’s antibacterial drug Xacduro in mainland China. The companies did not disclose the financial terms of the deal, which is slated to run through November 2028. The team-up comes as other drugmakers, like Merck, J&J and AstraZeneca, face challenges in the country.

After ALS trial misses mark, Seelos has filed for bankruptcy

After Seelos Therapeutics’ amyotrophic lateral sclerosis (ALS) candidate failed a phase 2/3 study, the biotech has filed for chapter 11 bankruptcy.

Calcium+Company enriches comms work with new commercial planning, market access division

New York-based health comms agency Calcium+Company is living up to its name, strengthening the bones of its business with the creation of a new division.

As J&J tries to wrap up US talc litigation, the company now faces threat of class action in UK

While Johnson & Johnson hopes to soon resolve more than 60,000 talc lawsuits with an $8 billion bankruptcy settlement in the United States, its baby power problems are only just beginning in the U.K. A British law firm representing 1,900 talc claimants has sent a letter to J&J, giving advance notice of a group-action lawsuit that it plans to file in the High Court in London, according to reports.

Engineered yeast cells deliver PD-1 inhibitors that shrink intestinal tumors in mice

Delivering drugs to gut tumors can be tricky. Researchers at Washington University in St. Louis have engineered an oral probiotic yeast to do the work for them, with the fungal cells able to release immune checkpoint inhibitors that shrank intestinal tumors in mice with colorectal cancer.

Roche's Vabysmo shows potential to treat eye disorder common in Asia

Interim results from a late-stage trial of Roche's Vabysmo on Asian patients with polypoidal choroidal vasculopathy suggest that the injected treatment is effective. After 16 weeks, patients showed vision improvement which was equivalent to reading roughly one and a half more lines on an eye chart.
 
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Industry Events

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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