To view this email as a web page, click here

November 30, 2016

Subscribe

Our Team

Contact Us

FierceBiotech Logo

 

Today's Rundown

  1. Arrowhead snaps after trial hold as it targets major layoffs, ditches programs

  2. Heptares to buy G7 to bolster GPCR capabilities

  3. Microbiome CNS upstart launches with $19.15M Series A

  4. Early data on OncoMed's cancer antibodies 'intriguing, but preliminary'

  5. Sanofi takes over Warp Drive antibiotic program

  6. Contract research worth £192M a year to U.K. NHS, says KPMG

  7. Nevro hits Boston Sci with patent infringement suit

  8. Novo's Tresiba could get market boost from new data on low blood sugar episodes

  9. Analysts say Sanofi plant failings could pose issues for 2 expected blockbusters

Featured Story

Arrowhead snaps after trial hold as it targets major layoffs, ditches programs

A few weeks back, and in fact the day before the U.S. election, RNAi biotech Arrowhead quietly posted some miserable news that its hep B candidate, ARC-520, was placed under a clinical hold by the FDA. Today, this candidate, along with a host of others and 30% of its staff, are to be axed as the biotech desperately seeks to refocus.


Top Stories

Heptares to buy G7 to bolster GPCR capabilities

Heptares Therapeutics is set to buy fellow European G protein-coupled receptor specialist G7 Therapeutics. The takeover will give Heptares access to additional technologies to stabilize GPCRs and a research outpost in Zurich, Switzerland.

Microbiome CNS upstart launches with $19.15M Series A

Longwood Fund and Domain Associates have led a $19.15 million funding round for newco Axial Biotherapeutics with the aim of creating new treatments for an array of CNS disorders by harnessing the gut microbiome.

Early data on OncoMed's cancer antibodies 'intriguing, but preliminary'

OncoMed has posted early data on two antibodies for cancer, but investors' eyes are still focused on prospects for cancer stem cell drug tarextumab.

Sanofi takes over Warp Drive antibiotic program

Sanofi has assumed responsibility for Warp Drive Bio's aminoglycoside antibiotic program. The handover happened after Warp Drive advanced the program against drug-resistant Gram-negative infections to a milestone defined in the $750 million pact the partners penned this year.

Contract research worth £192M a year to U.K. NHS, says KPMG

Carrying out contract clinical research for life science companies injects around £192 million into the U.K. National Health Service every year in income and cost-savings, says a new report.

Nevro hits Boston Sci with patent infringement suit

Almost exactly a year ago, the U.S. Patent and Trademark Office dismissed Boston Scientific’s challenges to Nevro’s patents for its spinal cord stimulation tech. Now, Nevro is hitting back, filing a patent infringement suit against Boston Sci.

Novo's Tresiba could get market boost from new data on low blood sugar episodes

Novo Nordisk has some new data showing that its long-acting insulin Tresiba results in significantly fewer nighttime low blood sugar episodes than its nemesis Lantus, while carrying about the same risk of serious heart issues, offering a spark of good news during a tough time for Danish drugmaker.  

Analysts say Sanofi plant failings could pose issues for 2 expected blockbusters

Sanofi and Regeneron are facing a possible delay on one potentially big drug, sarilumab, after receiving a complete response letter tied to manufacturing problems at a plant in France. But Leerink analysts think the plant’s shortcomings could spell issues for another potential blockbuster, dupilumab, an experimental, first-in-class treatment for eczema.

News of Note

The former head of Novartis’ drugs division David Epstein has signed up to become a "special advisor" to Remedy Pharmaceuticals. Release

Ferring Pharmaceuticals and Aché Laboratórios Farmacêuticos have joined forces to work on a nanotech research platform. Release

Ultragenyx has posted positive data from a midstage test of its UX007 in long-chain fatty acid oxidation disorder. Release

Cerecor says its phase 2 major depressive disorder test has failed, with next steps planned "at a later time." Release

 

Resources

[Infographic] Bridging the Patient ID Accuracy Gap

Get the stats you need to start down the path to a more secure infrastructure, today.

[Checklist] Customized Care Anywhere with Digital Signage

What's the first step to a better patient experience? The patient experience starts well before the exam room or even reception - it begins as soon as your patients pull into the parking structure.

[Whitepaper] The Paperless Future of Healthcare and Life Sciences

DocuSign’s eSignature solutions modernize healthcare and life science organizations by eliminating paper and antiquated signature processes while meeting compliance requirements and reducing costs and errors.

[Whitepaper] DocuSign Life Sciences eBook: Reducing Cycle Time with Digital Transaction Management

The patients who rely on your scientific leadership are expecting more.

[Whitepaper] Streamline Regulatory Compliance in Life Sciences with Digital Transaction Management

The U.S. Department of Justice has collected upwards of $17 billion in settlements from the healthcare industry since 2009, including more than $2 billion from a single life sciences company.

[Whitepaper] THE Rx FOR NEXT-GEN LIFE SCIENCES: How Technology Can Treat Industry Pain Points

Life sciences companies, like many industries today, face new challenges across the board. Read More.

[Research] Bioprocessing Services and Technologies Market Trends and Outsourcing Dynamics

Make essential outsourced bioprocessing decisions by staying informed of industry outsourcing practices and contract manufacturer usage patterns with ISR’s Bioprocessing Services and Technologies Market Trends and Outsourcing Dynamics report.

[Research] Biosimilars in the US Oncology Market (2nd Edition)

ISR’s Biosimilars in the US Oncology Market (2nd Edition) report provides data and insights from 101 US-based, board-certified oncologists/hematologist oncologists as to their expectations, fears, and aspirations for biosimilars in oncology.

[Research] Medical Science Liaisons in Oncology (2016)

Pinpoint the information oncologists find most valuable and the best sales channels for delivering specific types of data/information.

[Research] Bioprocessing Market Trends and Outsourcing Dynamics: 2016-2021

ISR’s Bioprocessing Market Trends and Outsourcing Dynamics: 2016-2021 report provides an overview of the current market dynamics for bioprocessing as well as an outlook on what the marketplace will look like in five years.

[Research] Phase II/III CRO Quality Benchmarking

ISR’s CRO Quality Benchmarking – Phase II/III Service Providers (8th Edition) report provides a Consumer Reports-style analysis of Phase II/III CRO service quality from hundreds of users who rated 44 Phase II/III CROs across 26 critical dimensions of quality.

[Whitepaper] Ensuring the Greatest Return From Your Poorly Soluble Molecule

Can you avoid a risky trial-and-error approach to find the right path for your poorly soluble molecule by utilizing a CDMO? Download this complimentary Whitepaper to learn more!

[Webinar] The Basics of Biotech 101, 201 & 301 - Price: $299

This 3-part webinar series is specifically geared toward the non-science professional who needs to better understand industry terminology, science, techniques and issues.

[Whitepaper] Complimentary IDMP Report from Gartner

Gartner research on short- and long-term strategies for IDMP compliance.

Events

.