| | By Angus Liu Eli Lilly has pushed back the deadline of its tender offer for radiotherapy company Point Biopharma’s shares for a second time. According to two senior executives, Lilly’s current predicament is caused not by any internal factors but by Point’s rival, Novartis. |
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By Kevin Dunleavy Novartis has gained the first of what it hopes are several FDA approvals for its factor B inhibitor iptacopan, dubbed two months ago “a pipeline in pill,” by analysts at ODDO BHF. The U.S. regulator has given a thumbs up to iptacopan to treat paroxysmal nocturnal hemoglobinuria (PNH). Known commercially as Fabhalta, it becomes the first oral monotherapy approved by the FDA for the rare blood disorder, which affects 10 to 20 people per one million worldwide. |
By Nick Paul Taylor Pfizer is continuing to pinball between oral obesity assets. Months after making twice-daily danuglipron its top prospect, the Big Pharma has dropped the program after more than half of people taking the drug candidate dropped out of a midphase clinical trial. |
By Fraiser Kansteiner During an enterprise business review Tuesday, J&J laid out a range of expectations across the 2025 to 2030 timeframe. Chief among those, J&J says it will boast more than 10 drugs with peak sales potential of at least $5 billion, plus another 15-plus products with sales potential of at least $1 billion. |
By Nick Paul Taylor Merck KGaA just sent shockwaves through the BTK inhibitor space. Evobrutinib, the German drugmaker’s contender for a blockbuster opportunity, failed to beat Sanofi’s Aubagio in two phase 3 multiple sclerosis (MS) clinical trials, raising doubts about the prospects of a clutch of heavily backed rival candidates. |
By Fraiser Kansteiner WuXi Biologics expects to miss its original sales target for the year by around $400 million, thanks to reductions across its development and manufacturing services. WuXi Bio blamed the projected miss largely on a COVID-related revenue slowdown and a decline in projects. |
By Andrea Park The FDA is looking into a spate of quality complaints regarding plastic syringes manufactured in China. |
By Angus Liu When it comes to expanding radiotherapy manufacturing capacity for Lutathera and Pluvicto, Novartis is putting its money where its mouth is. The Swiss pharma is investing about $85 million to build a new radiotherapy facility in China. |
By Helen Floersh Researchers have used unaltered human tracheal cells to create self-assembling multicellular robots capable of healing wounded neurons in a petri dish. |
By Ben Adams Swiss major Novartis is leaning on its roots as it launches a new look for the company after this year’s Sandoz spinoff and pipeline refocus. |
Fierce podcasts Don’t miss an episode |
| Earlier this year, Fierce Healthcare, Fierce Pharma and Fierce Biotech recognized 50 individuals and companies that are pushing the industry forward. The Fierce 50 winners range from tech innovators to researchers developing novel therapies to providers on the frontlines of changing care. This week on "Podnosis," senior editor Paige Minemyer sat down with staff writers Dave Muoio and Anastassia Gliadkovskaya as well as senior editor Heather Landi to discuss a few of the honorees in more detail. |
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Thursday, December 14, 2023 | 2pm ET/ 11am PT Many teams struggle to keep up with maintenance and breakdowns of critical equipment. Join this webinar to explore the root causes of these issues and discover how integrating essential elements can increase equipment uptime and process reliability. Register now. 
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