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December 12, 2018

Today's Rundown

Featured Story

Lilly pays AC Immune $81M upfront for preclinical Alzheimer’s drug

Eli Lilly has paid CHF 80 million ($81 million) upfront for the worldwide rights to AC Immune’s tau aggregation inhibitors in Alzheimer’s disease. The deal gives Lilly ownership of a small molecule that has inhibited tau aggregation in preclinical models.

Top Stories

NASH-focused Akero Therapeutics adds another $70M to the bank

The company has reeled in $70 million that will push its lead asset, a treatment for nonalcoholic steatohepatitis licensed from Amgen, through phase 2. Akero will also build out its metabolic disease pipeline and boost its manufacturing capabilities.

Casma names Third Rock venture partner as COO

Casma Therapeutics has named Third Rock Ventures’ Frank Gentile as its chief operating officer. The appointment means Gentile will commit full time to the autophagy startup he helped get off the ground.

GenSight rebuilds its case for LHON gene therapy, eyeing filing next year

GenSight Biologics has reported new data from its phase 3 program for GS010, its gene therapy for an ultrarare eye disease, sparking another uptick in its share price.

Roche to develop new dMMR pan-cancer test for Merck’s Keytruda immunotherapy

If you can’t beat 'em, join 'em: Roche is teaming up with its immuno-oncology competitor Merck & Co. to develop a pan-cancer companion diagnostic test for its Keytruda therapy aimed at detecting the mismatch repair deficiency biomarker, or dMMR, in solid tumors regardless of their location.

FDA clears first xenotransplantation trial of skin cells derived from genetically engineered pigs

The FDA has cleared XenoTherapeutics to begin a first-of-its-kind human clinical trial that uses topically applied live skin cells derived from genetically engineered pigs as a treatment for severe burns.

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[Report] Clinical Operations Report: Learn the Top Industrywide Priorities

Industry Research: Read the 2018 Unified Clinical Operations Report to find out how pharmas and CROs are evolving clinical trial processes.

[Webinar] QSP Approaches to Determine Best in Class Properties for Targeted Anabolic Growth Factor to Arthritic Joints

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[Research Report] Challenges And Opportunities In Clinical Data Management

New research reveals more than 50% of clinical data management professionals surveyed, are not confident in the quality and completeness of their clinical trial data.

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[Whitepaper] The Future of Cell & Gene Therapy

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[Whitepaper] Why Life Sciences Companies Leverage Managed Regulated Infrastructures

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[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

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