Top 10 healthcare M&A deals of 2021
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Today's Rundown

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Novartis cuts ties with Mesoblast's failed COVID-19 cell therapy as biotech tries for pivotal phase 3

Novartis has canceled an agreement with Mesoblast on a failed COVID-19 cell therapy just as the Australian biotech tries to get a new phase 3 trial off the ground in the hopes the FDA will give the candidate another shot. 

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Boston Scientific to lay off 170 workers, close Silicon Valley manufacturing plant

The manufacturing facility's closure and subsequent layoffs will take effect Jan. 30.

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The top 10 healthcare M&A deals of 2021

Healthcare merger and acquisition activity hit a new stride in 2021, fueled by investor interest in digital health and virtual care as well as the SPAC craze that's pumping a lot of cash into the market.

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CSL to buy Vifor for $11.7B in biopharma's largest M&A deal this year

In a move to diversify its business, Australian biopharma CSL has agreed to acquire Vifor Pharma for $11.7 billion. The deal would give CSL—heavily dependent on vaccines and blood plasma products—Vifor’s attractive kidney disease and iron deficiency franchises.

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Turns out Galera's radiotherapy complication drug did work after all, and investors are thrilled

Galera’s shares were pummeled in the wake of news that its radiotherapy complication drug flunked a phase 3 study, but now the biotech says the study results were in error, and the treatment did, in fact, work.

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Centene mulls divestiture of $2B international business as part of value creation effort

As part of its ongoing examination of its portfolio, Centene Corporation is "evaluating strategic alternatives" for its businesses abroad.

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Pfizer's COVID-19 antiviral is expected to work against the omicron variant

Pfizer said it expects its antiviral pill Paxlovid to provide protection against the omicron variant of the coronavirus, amid worldwide concern that existing medications and vaccines would not work against the newly mutated version.

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Philips gets the blood flowing with Vesper Medical vascular tuck-in buy

Philips is looking to bolster its vascular franchise by absorbing Vesper Medical, maker of stents designed to open up blocked or narrowed veins in the legs.

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Idorsia hoping to make its dreams come true with a new insomnia alliance

Sleepless nights are nothing new to most people, but chronic insomnia takes this to another level. Idorsia, awaiting an FDA approval for its sleep drug, has set up an alliance to research the condition.

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Fujifilm beefs up US biologics capacity with $300M Texas outlay, corrals 150 new jobs

Fujifilm Diosynth Biotechnologies is splashing out $300 million to build a new production facility at its single-use manufacturing campus in College Station, Texas, the company said Tuesday. Alongside a major biologics capacity upgrade, the expansion is set to add 150 new jobs by 2024—the same year that the new facility is expected to come online.

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Generation Bio shares halved as hemophilia gene therapy hunt goes back to square one

Generation Bio’s shares were briefly halted Tuesday morning on the release of mouse data that complicated its search for a viable target for hemophilia A to take into the clinic.

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Senate version of Build Back Better axes DSH cuts to hospitals in non-expansion states

A newly released version of the Build Back Better Act nixes cuts to disproportionate share hospital payments to facilities in states that did not expand Medicaid.

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FDA panel rejects BrainsGate neurostimulation implant for ischemic stroke

Nearly two years after BrainsGate submitted its implantable neurostimulation device for FDA premarket approval, an advisory panel for the agency struck a major blow to the Israeli company’s plans.

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Insurtech platform HealthCare.com banks $180M, boosts valuation to $1B

HealthCare.com, which connects consumers with health plans, is now a unicorn after closing a $180 million round that boosted its valuation to more than $1 billion.

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Sanofi's hemophilia hopeful reduces bleeds in phase 3 studies, but adverse events persist

Sanofi's hemophilia drug, put on pause last year, could be closer to the FDA's doorstep on new late-stage data that shows the treatment significantly reduced bleeds. But the adverse events that raised red flags are still persisting in one study.

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