Omega reels in largest biotech fund yet at $650M
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Today's Rundown

Featured Story

Ipsen ends 2021 deal spree with $543M biobucks tie-up for Genfit's liver disease drug

After a summer of deals, Ipsen is closing out the year with one last hurrah. The rare-disease-focused biopharma will partner with Genfit on a liver disease drug in a tie-up potentially worth a half-billion dollars over time.

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Top Stories

After FDA U-turn, Amylyx eyes IPO to support ALS drug filings across the world

Just like its approval request for a phase 2 ALS drug, Amylyx Pharmaceuticals is once again skirting convention and going forward with an initial public offering when the biotech market appears to be dipping.

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Omega, backer of 150-plus biotechs, lands 7th and largest fund at $650M to build new companies

With 150 biotechs to its name, Omega Funds closed its seventh and largest fund with $650 million to incubate drug developers, lead early financing rounds and back older startups on the brink of "cracking the problem."

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Sponsored: 7 Applications for Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Specimens

As technologies and methodologies advance, so do the potential applications for biospecimens. In this article, we explore seven uses of FFPE, ranging from the common to the cutting-edge.

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Pfizer joins $119M round for Novartis-backed cytokines biotech Anaveon to bankroll phase 2 studies

Pfizer and Novartis' venture arms have joined investment firms in backing a $119 million series B for Anaveon. The Swiss biotech will deploy the proceeds on a phase 1/2 study in solid tumors.

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Roche's Spark unit blueprints $575M gene therapy manufacturing center in Philly

Roche’s Spark Therapeutics unit is pitching $575 million into a new gene therapy manufacturing facility at Drexel University’s Philadelphia campus that will work towards the next generation of genetic medicines.

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Pfizer's peak COVID sales now pegged at $50B-plus, with vaccine still hauling in $25B by 2027: analysts

What do you get when you add the omicron variant to reduced effectiveness for Regeneron and Eli Lilly antibodies and a less-than-stellar report on Merck's ballyhooed antiviral? Mammoth sales for Pfizer's COVID-19 franchise, analysts say. Think $50 billion to $60 billion at peak—and a whopping $25 billion for the vaccine alone in 2027.

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Precisely targeting liver cancer with logic-gated gene therapy

Borrowing a concept from computation, scientists at ETH Zurich created genetic “logic gates” that can differentiate between tumor and nontumor cells based on their molecular profiles. A gene therapy using the system significantly reduced tumor burden in mice with liver cancer while sparing healthy cells.

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Allergan Aesthetics completes $550M Soliton buy following FTC probe

The deal folds Soliton’s flagship Resonic tattoo- and cellulite-removal device into the portfolio of AbbVie's medical aesthetics subsidiary.

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Biogen vows to contest EMA rejection of Aduhelm as EU regulators question weak link to Alzheimer's clinical benefit

Biogen knew what was coming: After a drug review committee's negative “trend vote,” a rejection of Aduhelm from EU authorities seemed inevitable. So when the rebuff did come, the biotech pounced.

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Oracle in talks to buy Cerner in potential $30B deal: WSJ

Oracle is in talks to buy healthcare IT giant Cerner, according to people familiar with the matter, a deal that could be worth around $30 billion, the Wall Street Journal reported.

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Fierce Pharma Asia—Merck, Eisai's failed Lenvima trial; J&J, Legend's CAR-T data; AstraZeneca-Samsung COVID pact

Merck and Eisai's Lenvima failed a Keytruda combo trial in newly diagnosed lung cancer. Johnson & Johnson and Legend Biotech's CAR-T posted a long tail to disease progression. AstraZeneca and Samsung Biologics included AZ's COVID antibody in their contract manufacturing deal. And more.

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Chutes & Ladders—Abbott's CEO and president is now also the medtech giant's chairman

Abbott CEO and President Robert Ford becomes chair of the board as two-decade leader Miles White retires. Gritstone's chief medical officer leaves to helm the same post at Neogene Therapeutics. Former Iterum Therapeutics vice president returns as chief medical officer after brief stint away.

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Resources

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Whitepaper: Demand Planning for New Drug/Device Combination

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A variety of genetic analysis methods are valuable in ensuring that ex vivo human cells to be used for cell-based therapies are correctly identified, have the correct characteristics, and are free of contaminants.

Research: How Buffer Prep Services Alleviate Sudden Spikes in Campaign Volume

Learn how a CDMO partnered with Thermo Fisher Scientific to manage high-volume process liquid and buffer preparation scale-up. Download the free case study from Thermo Fisher Scientific

Whitepaper: Modernizing Key Clinical Trial Processes with Artificial Intelligence

This whitepaper addresses where AI can make the biggest impact in clinical trials. The stakes are too high for patients to leave decision-making to machines, but AI can lend administrative support that empowers staff and medical experts alike to carry out their jobs more effectively.

Whitepaper: Medable was able to cut costs in multiple clinical trials by over US$25,000,000

Find out how to improve clinical protocol adherence, and thus patient outcomes, by 15%+ with Medable’s latest White Paper.

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Learn how to elevate your omnichannel marketing strategy with Next Best - a combination of data and analytics, deployed to facilitate decision making.

Webinar: The Faster Path From Pre-Filled Syringe to Auto-Injector

Ypsomed and Catalent Biologics experts discuss strategies for integrated PFS manufacturing and auto-injector assembly to accelerate timelines and more in this webinar.

Whitepaper: Formulation Strategies When Transitioning From Vial to PFS

Learn how formulation development for a PFS affects manufacturing to drive the industry toward optimizing delivery of injectable products and, ultimately, improving patient care.

2021 Report: Clinical Trial Management in a Post-Pandemic World

New market research provides valuable insight into the impact of adaptations made in clinical trials during the pandemic.

Whitepaper: Enhance the cost-effectiveness of your cGMP chemical supply chain

Learn how to develop a high-performing supply chain for cGMP chemicals used throughout your biologics workflow. Download the free whitepaper from Thermo Fisher Scientific

eBook: Get solutions to market faster

Read Get to Know Cloud Content Management for Life Sciences and learn how to eliminate silos across all workflows, from R&D to commercialization.

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