| Editor’s note: This is the last edition of Fierce PM Tracker for 2023. The Fierce team is taking a break from the regular newsletter schedule until Jan. 2, but be sure to check our sites for the biggest headlines until then. Enjoy your holiday season, and best wishes for the coming year. |
Today’s Big NewsDec 22, 2023 |
| By Annalee Armstrong Christmas has come early for Karuna Therapeutics’ shareholders. Bristol Myers Squibb has unwrapped a $14 billion deal to acquire the biotech, which sits on the cusp of having the first schizophrenia treatment approved in years. |
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By Zoey Becker The approval in hereditary transthyretin-mediated amyloid polyneuropathy, which affects around 40,000 to 50,000 patients globally, sets the stage for a potential label expansion down the line to treat the broader transthyretin amyloid cardiomyopathy patient population. |
By Andrea Park Commercial green lights have largely failed to translate into profitability for makers of digital therapeutics, many of whom found themselves struggling to stay afloat this year. |
By Gabrielle Masson It’s been a trying 2023 for Mersana Therapeutics and the year doesn’t appear to be ending on a high note. The antibody-drug conjugate (ADC) biotech and Merck KGaA have severed ties for a licensing pact related to one of Mersana’s tech platforms. |
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Tuesday, January 23, 2024 | 11am ET / 8am PT Join a cutting-edge conversation on January 23, 2024 with Real Chemistry and Quid as they explore how their partnership has forged a deeper understanding of patient insights. Register now. 
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By Eric Sagonowsky Based on the series of measures centered on U.S. drug prices coming out of Washington, the Biden administration is clearly emboldened on the topic. |
By Ayla Ellison,Annalee Armstrong,Gabrielle Masson This week on "The Top Line," Fierce Biotech staff writer Gabrielle Masson and senior editor Annalee Armstrong look back at the year in biotech, which was defined by massive layoffs across the industry. They also discuss their favorite stories of the year, including an appearance from a popstar whose reputation precedes her. |
By Angus Liu As the FDA investigates a safety signal for approved CAR-T therapies, the agency has elevated a warning about secondary cancers following the use of Johnson & Johnson and Legend Biotech’s Carvykti. |
By Conor Hale While AI has already made a deep impact on healthcare, the spotlight on programs such as ChatGPT has led to new debates on AI ethics and safety. |
By James Waldron AlloVir’s ambitions, like its share price, have shrunk significantly as the biotech abandons three late-stage trials of its lead asset after deciding none were likely to achieve success. |
By Kevin Dunleavy Even with the Federal Trade Commission keeping a watchful eye on the biopharma industry and the economic landscape giving some players pause, mergers and acquisitions are back on the rise. And it is with cautious optimism that industry watchers see the trend continuing in 2024. |
Fierce podcasts Don’t miss an episode |
| This week on "The Top Line," Fierce Biotech staff writer Gabrielle Masson and senior editor Annalee Armstrong look back at the year in biotech, which was defined by massive layoffs across the industry. They also discuss their favorite stories of the year, including an appearance from a popstar whose reputation precedes her. |
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