This week's Fierce Biotech is brought to you by Avantor.

Novel Cell Lysis Solution: Scaling up the harvest process while preserving what matters

Gene therapy promises to prevent, treat, and even cure inherited disorders. But manufacturing challenges—like outdated cell lysis solutions—are holding progress back. Chemical lysis is the preferred method for viral vector harvest, but current reagents fall short:

• Regulatory risks: Industry-preferred solutions are on the “substance of very high concern” list.
• Inefficiency: High viscosity, foaming, and damage to viral particles create inefficiencies.
• Complex handling: Excessive reagent volumes and storage limitations disrupt workflows.

Discover a novel biodegradable cell lysis reagent by downloading our free whitepaper that overcomes these challenges. With proven study data, it offers:

• Efficient viral vector release across varying cell densities and temperatures.
• Protection of viral particles from damage during agitation.
• Streamlined processes with reduced viscosity, foaming, and room-temperature stability.

Ready to unlock scalable, consistent, and sustainable viral vector manufacturing? Break through manufacturing challenges with our new whitepaper designed for today’s gene therapy needs.