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Eli Lilly’s next-gen GLP-1 moves the needle in early-stage diabetes ahead of FDA filing

Chalk another one up for Eli Lilly’s next-generation diabetes drug. All three doses of tirzepatide beat placebo at lowering blood sugar and body weight in adults with early-stage Type 2 diabetes, more than half of whom had never tried a diabetes-specific treatment.

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Novo trumpets higher-dose Ozempic data as Lilly competitors loom

Novo Nordisk has data showing 2-mg Ozempic topped its lower-dose predecessor on blood sugar and weight reduction. Side effects were on par with the lower dose, too, which could quiet analyst concerns about the potential popularity of stronger GLP-1 meds.

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After strong showing for Soliqua against premixed insulin, Sanofi exec expects 'a lot of interest' among doctors

Years ago, Sanofi's Soliqua hit the diabetes market with the promise of combining an insulin and a GLP-1 medicine in a convenient once-daily treatment option. So far, though, sales haven't quite matched that promise. With new data, Sanofi is hoping to change that.

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Hanmi’s GLP-1 drug, returned by Sanofi, curbs cardiovascular, kidney issues while tackling Type 2 diabetes

Hanmi Pharmaceuticals may no longer have a diabetes partner in Sanofi, but newly released results for its GLP-1 drug could move the needle for Type 2 diabetes patients with a history of cardiovascular disease, kidney disease or both. Efpeglenatide reduced their risk of heart attack, stroke and death and also slowed decline in patients’ kidney function, new data show.

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AstraZeneca touts Bydureon trial win in children and adolescents with type 2 diabetes

At the American Diabetes Association’s Scientific Sessions, AstraZeneca presented positive results of a phase 3 trial of Bydureon, the first to be completed by a once-weekly GLP-1 receptor agonist on children and adolescents with type 2 diabetes.

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Senseonics shows off accuracy of its six-month implanted glucose sensor

Though the review of its 180-day implantable glucose sensor has faced FDA delays during the COVID-19 pandemic, Senseonics was able to deliver clinical data on its accuracy at two diabetes meetings this month.

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TB vaccine repurposed in Type 1 diabetes restores gene expression in key immune cells

Researchers at Massachusetts General Hospital have spent the last two decades building up data to support their idea of repurposing the old tuberculosis vaccine BCG in type 1 diabetes. Now they have new data backing up their finding that the vaccine restores the ability of regulatory T cells (Tregs) to prevent the destruction of insulin-producing pancreatic islets.

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Insulet's automated Omnipod drops HbA1c in preschoolers with Type 1 diabetes

For young children with Type 1 diabetes and their parents, Insulet hopes its newest artificial pancreas system can make the “terrible twos” a little more manageable for everyone.

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Medtronic's smart insulin pen helps control blood sugar levels in study

Medtronic’s smart insulin pen doesn’t merely provide the convenience of a one-stop shop for diabetes management—according to newly released data, it’s also highly effective at regulating blood sugar levels and reducing instances of hypoglycemia.

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