Biofabrication is a revolutionizing toolkit for regenerative medicine that allows cells and other biomaterials to be precisely combined and patterned into three-dimensional (3D) constructs through automated, cell-friendly fabrication methods. With rapid advanced in 3D-printing hardware on one hand and bioink materials on the other, biofabrication techniques have gained significant momentum and provide a powerful approach to tackle major hurdles in the generation of engineered living tissues. While 3D bioprinting is still in its early stages, the remarkable leap it has made in recent years points to the eventual reality of lab-grown, functional organs.