DNA is probably the most programmable biomaterial for creating a wide range of rationally designed and functionally enhanced nanostructures. The sophisticated, programmable, and addressable DNA nanostructures are strong candidates for constructing nanoelectronic devices. The size of DNA molecules is also key: DNA double-helix has a neighboring base pair distance of 0.34 nm and a diameter of 2.1 - 2.6 nm a, and thus DNA complex-based nanoelectronics may break the 5-nm processing limit of commercial silicon-based semiconductors.
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