Boeing’s Starliner spacecraft blasted off with astronauts onboard for the first time, kicking off a high-stakes test flight to the International Space Station.

The Starliner’s first crewed flight comes after many delays and setbacks. If successful all the way through its return to Earth, it could pave the way for Boeing to fly regular missions for NASA and finally catch up to Elon Musk’s SpaceX, which has been flying astronauts to the space station since 2020.