CAR-T therapies have shown tremendous clinical potential. However, the manufacturing remains challenging due to the lack of control and automation as well as process and cell product characterization during process development and manufacturing stages. In this edition of Experts’ Insights in Advanced Therapies, Dr. Qasim Rafiq, Associate Professor of Bioprocessing Engineering at UCL shares his insights from the development of an automated CAR-T expansion process.

Read to find out about:

• Scalable stirred-tank CAR-T cell expansion
• Optimizing cell product quality through process insight
• The future of CAR-T manufacturing to reduce batch variation, batch failure, and process cost