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| | | Metabolic measurement of humans and animal models is an important aspect of biomedicine. However, the limitations of current methods in metabolic measurement are not widely understood. This mini-review explains the methodological trade-offs involved in metabolic measurement with flow-through respirometry and specifically addresses limitations regarding temporal resolution and accuracy of metabolic measurement systems with practical solutions. | |
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| | FEATURED STORY | | The Food and Drug Administration has approved the drug Radicava, also known as edaravone, for the treatment for amyotrophic lateral sclerosis (ALS). This is the first time an ALS drug has been cleared for use in the U.S. since the drug riluzole was approved in 1995.
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| | | | Due to an increase in the abuse of synthetic insulins, doping laboratories require faster and more consistent testing options. The methodology to detect and confirm the presence of peptide hormones by mass spectrometry is preferred to the current use of immunoassays or other immuno-reactive techniques. This white paper explores and compares the different available methods, revealing the fastest and most accurate options for synthetic insulin detection.
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| | NEWS | | In preclinical studies, researchers found adoptive T cell therapy was more effective against melanoma when combined with common platelet-inhibitors, such as aspirin.
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| | NEWS | | A gene mutation may speed up memory loss and cognitive decline in people at risk for Alzheimer's disease, a new study found.
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| | | | Utilizing benchtop flow cytometry, new novel multicell GFP reporter assay was developed to help facilitate discrimination between induction of DNA damage, oxidative stress and protein misfolding.
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| | FOCUS ON: | | Detecting changes in apolipoprotein levels can be difficult with traditional ELISA techniques because they require a large sample input. Bio-Rad developed the Pro Apolipoprotein Panel as a multiplex solution to this problem.
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| | NEWS | | New safety risks were identified for nearly one out of every three drugs approved by the Food and Drug Administration (FDA) in the years following approval, according to a new analysis.
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| | NEWS | | Fruit flies typically depend on yeast as a main protein source, but have a natural tendency to seek out a quick fix of sugar. New research has found a small set of brain cells, called dopamine wedge neurons, are responsible for influencing the insects to crave yeast once they've been deprived of the nutrient.
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| | NEWS | | The first analysis of how proteins are arranged in a cell has been published, revealing that a large portion of human proteins can be found in more than one location in a given cell.
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| | NEWS | | A new study shows that the behavior of stem cells in plants and animals is surprisingly similar. The researchers were able to produce mathematical equations that reveal very small differences in the behavior of the proteins and the results can potentially be used in stem cell research involving humans.
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| | NEWS | | Researchers led the most powerful genomic study of anorexia nervosa conducted to date to identify the common roots anorexia shares with psychiatric and metabolic traits.
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| | NEWS | | One person has been confirmed dead from Ebola in an outbreak in a remote corner of northern Congo as health authorities look into a total of nine suspected cases, including two other deaths, the country's health minister and the World Health Organization said Friday.
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