Gestational Diabetes and Related Outcomes in Singleton and Twin Pregnancies

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Plus: Six types of prediabetes; potato-based diets; reducing heart risk

Saturday, Jan. 16, 2021 : Issue #1098

TOP STORIES - Diabetes News & Research

Major Reduction in Risk of Heart Attacks in Patients with Diabetes
How Patients With T2DM Can Safely Consume Food With High Glycemic Index
Gestational Diabetes and Related Outcomes in Singleton and Twin Pregnancies

Letter from the Editor
Although every news day is filled with information about COVID-19, patient deaths and the seemingly snail's pace of vaccinations, only one illness has seemingly been positively affected by the corona virus, and that is the flu. It appears that the use of masks, social distancing, and fewer sick people in the workplace has reduced the incidence of the flu by over 40%. However, other diseases like diabetes and heart disease have not slowed down and appear to be worsening as well.
This week our intern from South College of Pharmacy, Destiny Funchess, has a great article on how best to treat your diabetes patients to prevent a cardiovascular accident.
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We can make a difference!
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Dave Joffe
Editor-in-chief

Fact: The Six Distinct Types of Prediabetes

Scientists have, for the first time, distinguished six different subtypes of prediabetes. The research, tracking data from an intensive 25-year longitudinal study, suggests these new subtypes will allow clinicians to identify those patients most likely to develop diabetes and provide the most effective treatment for each subtype. It has not been possible for people with prediabetes until now to predict whether they would develop diabetes and be at risk of severe complications such as kidney failure, or whether they would only have a harmless form with slightly higher blood glucose levels without significant risk.
Using a method called cluster analysis, the research homed in on six different prediabetes subtypes, each distinguished by other metabolic markers.
Image: DZD Institute for Diabetes Research and Metabolic Diseases (IDM) of Helmholtz Zentrum München at the University of Tübingen
Each of the six prediabetes subtypes is distinguished by specific metabolic parameters and results in different long-term outcomes. Three subtypes (clusters 1, 2, and 4) are the healthiest types of prediabetes. These subjects present as generally healthy. Cluster 4, for example, encompasses overweight subjects with broadly healthy metabolic markers. Clusters 3, 5, and 6 were linked to the highest risk of developing type 2 diabetes and secondary diseases. Cluster 5 grouped those subjects with pronounced fatty liver, while cluster 3 grouped those who produced significantly lower insulin levels.
In another study, the researchers examined data from another longitudinal study. Called Whitehall II, the UK study tracked nearly 10,000 subjects' metabolic health for over 20 years. The six subtypes accurately fit that large dataset, affirming prediabetes can be distinguished into separate disease stratifications. One of the goals is to develop precise prevention and therapy measures, i.e., the appropriate prevention or treatment for the right group of people at the right time.
The new study was published in the journal Nature Medicine, Jan 2021

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:

Abdullah Al-Ajmi, PharmD Candidate, Skaggs School of Pharmacy and Pharmaceutical Sciences

Brianna Belton, PharmD. Candidate, Florida Agricultural & Mechanical University, College of Pharmacy and Pharmaceutical Sciences

Destiny Funchess, PharmD Candidate, Tougaloo College, South College School of Pharmacy

Aleksandra Kusic, PharmD Candidate, Florida A&M University, College of Pharmacy and Pharmaceutical Sciences

Arjay Mendoza, PharmD Candidate, University of Colorado Denver Skaggs School of Pharmacy and Pharmaceutical Sciences

Sandra Zaki, PharmD Candidate, Florida A&M University

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Your Friends in Diabetes Care
Steve and Dave
Diabetes In Control
www.diabetesincontrol.com

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Gestational Diabetes and Related Outcomes in Singleton and Twin Pregnancies

Saturday, Jan. 16, 2021 : Issue #1098

TOP STORIES - Diabetes News & Research

TOP STORIES - Diabetes News and Research

Fact: The Six Distinct Types of Prediabetes

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:

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