| Commuter and recreational cycling was consistently associated with lower risk of T2D in Danish adults. Our results also provide evidence that late-in-life initiation of or continued engagement in cycling lowers risk of T2D (PLoS Medicine)
This quality standard covers the diagnosis and management of type 1 and type 2 diabetes in children and young people aged under 18 (NICE)
In a real-world clinical setting, people with Type 2 diabetes mellitus initiating glucose-lowering medication had a similar likelihood of achieving glycaemic control, regardless of sex, age, comorbidities and other individual factors; the only strong and potentially modifiable predictor was HbA1c before therapy starts (Diabetic Medicine)
With the prevalence of Type 2 Diabetes Mellitus (T2DM) continuing to rise in most high-income, low-income, and middle-income countries [1], strategies to stem the emerging pandemic are urgently needed (PLoS Medicine)
Targeted diabetes screening based on new USPSTF criteria may detect approximately half of adult community health center patients with undiagnosed dysglycemia and proportionately fewer racial/ethnic minorities than whites. Future research is needed to estimate the performance of these screening criteria in population-based samples (PLoS Medicine)
This study suggests that being retained/engaged in a relatively low-resource, pragmatic diabetes prevention programme for those at high risk is associated with reductions in the progression to T2DM in comparison to those who receive standard care. Nonengagers and nonretainers share similar high-risk traits. Service providers of programmes should focus on reaching these hard-to-reach groups (PLoS Medicine)
Our meta-analysis based on available RCT data does not support the harm effect of SGLT2 inhibitors on fracture, although future safety monitoring from RCT and real-world data with detailed information on bone health is warranted (Diabetes, Obesity and Metabolism)
This review will evaluate the effects of diabetes self management interventions for people with severe mental illness and type 2 diabetes, and it will provide us with the opportunity to describe, using established reporting systems, the active components of these interventions and the theoretical frameworks within which they were developed to establish how they work (Cochrane)
This guideline covers the assessment and care of adults who are at risk of or who have cardiovascular disease (CVD), such as heart disease and stroke. It aims to help healthcare professionals identify people who are at risk of cardiovascular problems. including people with type 1 or type 2 diabetes, or chronic kidney disease (NICE)
Elevated morning blood ketones are more common in younger children with type 1 diabetes with or without nocturnal insulin suspension. Care providers need to be aware of the differences in ketogenesis in younger age children relative to various clinical situations(Pediatric Diabetes)
There is no significant evidence of long term efficacy of insulin on any clinical outcome in T2D. However, there is a trend to clinically harmful adverse effects such as hypoglycaemia and weight gain. The only benefit could be limited to reducing short term hyperglycemia. This needs to be confirmed with further studies (BMC Endocrine Disorders)
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