Glycosmedia Weekly Diabetes News Update
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Glycosmedia Weekly Diabetes News - 06/24/2016

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Could we ask your opinion on the new Editorials. Do you value them? Shall we continue with them? Or not?

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Editorial opinion

Given the epidemiology of diabetes, it is understandable that there is a shift in routine management from secondary to primary care. Whether there is enough support for primary care is debatable but usually there is enough guidance to manage non insulin treated patients – and even those on non complex insulin regimes. So far so good! However, there is a risk that patients with T1DM may get caught up in the rush to transfer care out of hospital. In fact, this week’s episode of Pulse describes a commissioning intention of a CCG to actively promote it.

However, it is often not understood that T1 and T2 diabetes behave like two separate conditions when it comes to glucose lowering. Furthermore, there is a major difference in the education that these patients require, specifically the intricacies of carbohydrate counting, correction doses and the detailed awareness of the profiles of a variety of rapid and longer acting insulin, not to mention pump therapy.  Type 1 patients often possess. There is also the higher risk of hypoglycaemia including unawareness with all the associated issues including the impact on driving.

Whilst it is possible that practices have the skills to manage T1 patients, it is unlikely that this can be done without significant support from specialist care. This can come in a variety of ways including education sessions, virtual or e-consultation to name a couple. It is unclear from the proposals as to how this will be done. Furthermore, there is no acknowledgement that T1 patients are often highly motivated and educated about their condition, commonly having more knowledge about ‘their’ diabetes than the health care professional treating them. Significant input would be necessary to convince these patients that the transfer of care does not come at the expense of clinical care.

Overall, the location of care is not important, ensuring that the right patient is seen by the right clinician is vital to ensure that this group of patients are not disadvantaged.

Dr. Mark Freeman


Individualized prediction of the effect of angiotensin receptor inhibition on renal and cardiovascular outcomes in patients with diabetic nephropathy

The combined effects of ARBs on ESRD and CVD and mortality in patients with diabetic nephropathy varies considerably between patients. A substantial proportion of patients remain at high risk for both outcomes despite ARB treatment (Diabetes, Obesity and Metabolism)


Update and Next Steps for Real-World Translation of Interventions for Type 2 Diabetes Prevention

Reflections From a Diabetes Care Editors’ Expert Forum


Long-term excess mortality associated with diabetes following acute myocardial infarction: a population-based cohort study

At index acute myocardial infarction, diabetes was common and associated with significant long-term excess mortality, over and above the effects of comorbidities, risk factors and cardiovascular treatments (Journal of Epidemiology & Community Health)


The evolving frontier of diabetes therapy: the renaissance of glycemology

A modern, updated approach to glycaemic control in people with diabetes, in fact, must focus not only on reaching and maintaining optimal HbA1c levels as soon as possible, but to obtain this result by reducing postprandial hyperglycaemia and glycaemic variability, while avoiding hypoglycaemia (Diabetes Research and Clinical Practice)


Ocular surface disease in patients with diabetic peripheral neuropathy

This study demonstrates some increased clinical signs of ocular surface disease but not an increase in subjective symptoms of dry eyes, with increasing severity of DPN (British Journal of Ophthalmology)


Plant-Based Dietary Patterns and Incidence of Type 2 Diabetes in US Men and Women

Our study suggests that plant-based diets, especially when rich in high-quality plant foods, are associated with substantially lower risk of developing T2D. This supports current recommendations to shift to diets rich in healthy plant foods, with lower intake of less healthy plant and animal foods (PLoS Medicine)


Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus

Long-term pioglitazone treatment is safe and effective in patients with prediabetes or T2DM and NASH (Annals of Internal Medicine)


The Artificial Pancreas in 2016: A Digital Treatment Ecosystem for Diabetes

This issue of Diabetes Care presents today’s AP state of the art, including reports on multinational home-use AP trials, studies in young children, the use of multihormonal approaches to mitigate meal-related hyperglycemia, and discussions of AP study designs and outcome measure (Diabetes Care)


Type 2 Diabetes Remission Rates After Laparoscopic Gastric Bypass and Gastric Banding

Diabetes remission up to 3 years after RYGBP and LAGB was proportionally higher with increasing postsurgical weight loss. However, the nearly twofold greater weight loss–adjusted likelihood of diabetes remission in subjects undergoing RYGBP than LAGB suggests unique mechanisms contributing to improved glucose metabolism beyond weight loss after RYGBP (Diabetes Care)


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Please visit the Glycosmedia website for more features and information, including:

Journal Watch
Comment on recently published papers written by the medical editors of Glycosmedia.

Diabetes Updates
Updates written by Professor Steve Bain (Diabetologist) and Dr. Mark Freeman (Diabetologist).

Book and Product Reviews
A selection of book and product reviews written by the contributing editors of Glycosmedia.
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