Glycosmedia Weekly Diabetes News - 02/07/2020

Progression of Insulin Resistance: A Link between Risk Factors and the Incidence of Diabetes

Change of IR can be used as a surrogate marker of incident diabetes. The progression of IR is an important pathophysiologic link between risk factors and the incidence of diabetes (Diabetes Research and Clinical Practice)

Time-varying risk of microvascular complications in latent autoimmune diabetes of adulthood compared with type 2 diabetes in adults

At diabetes onset, adults with latent autoimmune diabetes have a lower risk of microvascular complications followed by a later higher risk of complications than do adults with type 2 diabetes, secondary to worse glycaemic control (The Lancet Diabetes & Endocrinology)

Sodium‐Glucose Cotransporter 2 Inhibition for the Prevention of Cardiovascular Events in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta‐Analysis

Sodium‐glucose cotransporter 2 inhibitors protect against cardiovascular disease and death in diverse subsets of patients with type 2 diabetes mellitus regardless of cardiovascular disease history (Journal of the American Heart Association)

The Relationship between Self‐Monitored Blood Glucose Values and Glycated haemoglobin in Insulin‐treated Patients with Type 2 Diabetes

These data provide patients and clinicians information on the relationship between HbA1c and SMBG measurements in patients with type 2 DM, and support the value of frequent blood glucose measurements for assessing overall glycaemic control (Diabetic Medicine)

The changing prevalence of diagnosed diabetes and its associated vascular complications in a health district of the United Kingdom

The prevalence of identified diabetes appears to have increased substantially over a relatively short period of eight years to 2004. The increase in prevalence was 46%, with an increase in numbers of patients with diabetes of 53%. A number of factors are likely to have contributed to this, including an increase in case ascertainment (Diabetic Medicine)

Daytime variability of postprandial glucose tolerance and pancreatic beta‐cell function using 12 hour profiles in persons with type 2 diabetes

There appears to be a shift in diurnal variation in glucose homeostasis and pancreatic beta‐cell function. Subjects had decreased glucose tolerance in response to the first and third meal of the day irrespective of glycaemic control. The variability in glucose tolerance was reflected by both quantitative and qualitative dysfunction of the pancreatic beta‐cell (Diabetic Medicine)

BSPED Interim Guideline for the Management of Children and Young People under the age of 18 years with Diabetic Ketoacidosis

These BSPED guidelines are believed to be as safe as possible in the light of current evidence.However, no guidelines can be considered entirely safe as complications may still arise. In particularthe pathophysiology of cerebral oedema is still poorly understood (the British Society for Paediatric Endocrinology and Diabetes)

IWGDF Guidelines on the prevention and management of diabetic foot disease

The International working Group on the Diabetic Foot (IWGDF) has been producing evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. In 2019, all IWGDF Guidelines have been updated, based on systematic reviews of the literature and formulation of recommendations by multidisciplinary experts from all over the world (International Working Group on the Diabetic Foot (IWGDF) )